Acute hypertensive crisis with myoclonic movements induced by withdrawal of intrathecal combined clonidine and morphine administration
Objective: Clonidine is a centrally acting alpha(2)-agonist antihypertensive drug used for opioid/alcohol withdrawal and for intrathecal administration in the treatment of chronic neuropathic pain. Cases…Treatment of subcutaneous nodules after subcutaneous infusion of apomorphine
Objective: To evaluate the efficacy of 4 treatment modalities on apomorphine-induced subcutaneous nodules as compared to no treatment. Background: Subcutaneous nodules are the most common adverse events…Effect of gastrointestinal surgery on the pharmacokinetics of levodopa in Parkinson’s disease
Objective: The aim of this study is to evaluate the pharmacokinetics of levodopa in patients with Parkinson’s disease (PD) who underwent gastrointestinal surgery. Background: Levodopa…Neuropsychiatric manifestations in Parkinson’s disease
Objective: Evaluate the different neuropsychiatric manifestations in Parkinson's disease. Background: Parkinson's disease (PD) is the second most common neurodegenerative pathology after Alzheimer's disease, although PD…Prevalence and risk factors for impulsive compulsive behaviors in a cohort of Parkinson’s disease patients
Objective: Objective of the study was to analyze the risk factors for the development of these behaviors. Background: Impulsive compulsive behaviors (ICBs) are a frequent…Altered intrinsic power spectral density of the precuneus in patients with hyperkinetic functional movement disorders
Objective: In order to better understand the underlying mechanisms of functional movement disorders (FMD), we set out to explore changes in functional connectivity and intrinsic…Early onset parkinsonism and optic atrophy due to SLC25A46 mutations
Objective: To define the genetic background of a case affected by parkinsonism with optic atrophy. Background: Mutations in SLC25A46 have been recently described as causative…Parkinsonism and other motor features in familial frontotemporal dementia with mutations in the MAPT, GRN, or C9orf72 gene (LEFFTDS cohort)
Objective: We compared motor features in patients with familial frontotemporal dementia (f-FTD) and MAPT, GRN or C9orf72 gene mutations. Special emphasis was placed on the evaluation…Reverse phenotyping of a 3.3Mb loss of 8p11.21p11.1, including SLC20A2, lead to a diagnosis of primary familial brain calcification
Objective: To describe the clinical picture of a patient with a large deletion in band 8p11.21p11.1 including SLC20A2 and present a review of patients with a…Gene panel testing in movement disorders: an efficient approach highlighting overlaps and heterogeneity
Objective: Our study aimed at developing a targeted sequencing approach using a customized panel of genes involved in movement disorders (MDs). Background: MDs are characterized…
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