Parkinson Disease Clinical Subtypes Predict Dementia and Mortality Risk
Objective: To identify PD clinical subtypes based on patterns of motor, cognitive, and psychiatric symptoms; to assess the clinical utility of each subtype in predicting…Safety and Tolerability of Apomorphine Sublingual Film During Maintenance Treatment in Patients With Parkinson’s Disease and “OFF” Episodes: A Pooled Analysis
Objective: To examine safety and tolerability of apomorphine sublingual film (APL-130277; APL) during maintenance treatment using pooled data from 4 clinical studies in patients with…Deep Brain Stimulation Wash-in/out Periods Quantified using a Palm-Worn Device to Monitor Rigidity
Objective: Characterize the temporal resurgence/amelioration of Parkinsonian rigidity corresponding to withdrawal/application of deep brain stimulation (DBS) therapy. Background: Rigidity is a cardinal symptom of Parkinson’s…A general impaired-rhythm system underpins oro-motor, manual, and gait rhythmic disturbances in Parkinson’s disease
Objective: To assess whether rhythmic disturbances in three different domains (i.e., oro-motor, finger tapping and gait domains) are related in Parkinson's disease (PD), and to…Abnormal metabolic brain network in multiple system atrophy and progressive supranuclear palsy: a replication on a new European cohort
Objective: To identify characteristic metabolic brain patterns specific for multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) in a new cohort of patients and…Protective effects of β-Nicotinamide Adenine Dinucleotide against motor deficits and dopaminergic neuronal damage in a Parkinson’s disease mouse model
Objective: The aim of our study is to explore whether nicotinamide adenine dinucleotide (NAD) replenishment could be beneficial on a 6-hydroxydopamine-induced Parkinson’s disease (PD) mouse…Hypothalamic functional connectivity correlates with autonomic symptom burden in patients with Multiple System Atrophy
Objective: To investigate the association between autonomic symptom burden and hypothalamic functional connectivity in patients with MSA. Background: Multiple system atrophy (MSA) is a progressive…Medical and Device-Guided Therapies and Deep Brain Stimulation in Parkinson’s disease: Experience of a Tertiary Centre from Turkey
Objective: This study is aimed to investigate the clinical and therapeutic data of PD patients who have been evaluated at a dedicated-weekly Movement Disorders Clinic. Details…Cough sensitivity and aspiration pneumonia in Parkinson’s disease
Objective: We hypothesized that decreased cough sensitivity is crucial to the development of aspiration pneumonia in Parkinson’s disease (PD). We examined the relationship between cough…Identifying genetic Parkinson’s disease patients worldwide: Exploiting novel ways of team science
Objective: To identify a worldwide cohort of patients and families with genetic Parkinson’s disease (PD) as an example of a new, comprehensive approach to global…
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