MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Effects of Handwriting Exercise on Functional Outcome in Parkinson’s Disease: A Randomized Controlled Trial

    N. Vorasoot, P. Termsarasab, K. Thadanipon, T. Pulkes (Bangkok, Thailand)

    Objective: To determine whether handwriting exercise could improve writing skill and fine manual function in Parkinson’s disease (PD). Background: PD patients frequently experience micrographia, difficulty…
  • 2019 International Congress

    Restless legs syndrome in a patient with hereditary hemochromatosis

    Z. Fatima, S. Wijemanne (San Antonio, TX, USA)

    Objective: We present a case with two disorders, hereditary hemochromatosis (HH) and Restless Legs Syndrome (RLS), each related to the two ends of the spectrum…
  • 2019 International Congress

    The Clinical Features of Parkinson’s Disease with 20 Years or More Survival

    JJ. Lin, KC. Yueh (Nantou, Taiwan)

    Objective: To evaluate the clinical demographic data in Parkinson’s disease (PD) survivors with 20 years duration and beyond (PD-20) and investigate the impact of age…
  • 2019 International Congress

    A randomised rater-blinded study of motor consequences of inactivity in Parkinson’s disease revealing a new phenomenon: Stasis Induced Akinesia

    M. Schumacher, S. Tisch (Sydney, Australia)

    Objective: To evaluate experimentally the effects of prolonged sedentary inactivity on Parkinson’s disease (PD) motor function. Background: A frequently described but hitherto unreported symptom among…
  • 2019 International Congress

    Successful altruistic living kidney donation in a patient with Huntington’s disease

    C. Cooper, S. Chen, B. Bernard, J. Goldman (Chicago, IL, USA)

    Objective: To report a case of a Huntington’s Disease (HD) patient who underwent living kidney donation and examine the decision-making process and ethical considerations of…
  • 2019 International Congress

    Magnetic Resonance Spectroscopy Evaluation of Neuronal Integrity and Astrocytosis in a Phase 2 Study of Laquinimod as a Treatment for Huntington Disease (LEGATO-HD)

    B. Leavitt, R. Reilmann, M. Gordon, K. Anderson, A. Feigin, S. Tabrizi, J. Stout, P. Piccini, B. Russell-Schulz, A. Mackay, B. Borowsky, G. Rynkowski, R. Volkinshtein, J. Savola, M. Hayden (Vancouver, BC, Canada)

    Objective: Evaluate the effect of laquinimod on putaminal and frontal white matter markers of neuronal integrity and astrocytosis using magnetic resonance spectroscopy (MRS) in patients…
  • 2019 International Congress

    Mobility Impairments in Huntington’s Disease due to Cognitive Dysfunction

    M. Rakhimova, N. Yusupova (Tashkent, Uzbekistan)

    Objective: This study examined the relationships of mobility, motor and cognitive function measures at baseline, and of mobility and cognitive measures over four years Background:…
  • 2019 International Congress

    Prolonged-release Melatonin for Sleep Disorders in Parkinson’s Disease: A Randomized trial

    JH. Ahn, M. Kim, JK. Mun, J. Youn, S. Park, W. Jang, J. Park, E. Oh, JW. Cho, JS. Kim (Seoul, Republic of Korea)

    Objective: To evaluate the efficacy of PRM in sleep disorders of patients with PD was investigated. Background: Sleep disorders are highly prevalent in patients with…
  • 2019 International Congress

    Enabling efficient use of digital health technologies to support Parkinson’s disease drug development through precompetitive collaboration

    J. Cedarbaum, K. Taylor, D. Hill, R. Alexander, Y. Luo, R. Rubens, N. Zach, J. Cosman, A. Dowling, K. Fisher, L. Oliva, J. Hitchcock, M. Lawton, D. Conrado, K. Romero, M. Minchik, D. Meulien, B. Yang, M. Forman, L. Bataille, D. Dexter, J. Gallagher, M. Braxenthaler, M. Lindemann, B. Boroojerdi, G. Stebbins, B. Bloem, M. Hu, E. Dorsey, D. Stephenson (Cambridge, MA, USA)

    Objective: To describe the Critical Path for Parkinson’s (CPP) consortium approach to advance the field of digital technologies in clinical drug development for Parkinson’s disease…
  • 2019 International Congress

    Dopamine receptor variants alter outcomes with levodopa in early-stage Parkinson’s disease

    D. Fischer, P. Auinger, J. Goudreau, A. Cole-Strauss, K. Kieburtz, J. Elm, M. Hacker, P. Charles, J. Lipton, B. Pickut, C. Sortwell (Grand Rapids, MI, USA)

    Objective: To examine if specific single nucleotide polymorphisms (SNPs) in the genes for dopamine receptors 2 and 3 (DRD2, DRD3) correlate with worse outcomes within specific…
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