The short-term effect of combined facial exercise with botulinum toxin A injection in clinical practice in Thai patients with hemifacial spasm: A randomized controlled pilot crossover study
Objective: To compare the efficacy of combined facial exercise with BTX-A injection with BTX-A injection alone measured by the total HFS-30 (tHFS-30) score. Background: Hemifacial…The mGlu2/3 orthosteric antagonist LY-341,495 abolishes the anti-dyskinetic and anti-psychotic effects of the mGlu2 positive allosteric modulator LY-487,379 in the MPTP-lesioned marmoset
Objective: We seek to determine the effect of orthosteric blockade of metabotropic glutamate 2 and 3 (mGlu2/3) receptors with LY-341,495 on the anti-dyskinetic and anti-psychotic…Preclinical profile of dopamine D1PAM: A novel mechanism in clinical development for Lewy Body dementia
Objective: Introduce the mechanism of action for dopamine D1 positive allosteric modulator (D1PAM) as a new target for neuropsychiatric disorders. Describe the preclinical profile of…Prospective study on impulsive-compulsive behaviours in early Parkinson’s disease
Objective: To assess longitudinally impulsive-compulsive behaviours (ICBs) in a cohort of Parkinson's disease (PD) patients at the initial stage of the disease during 5 years…The effect of intranasal oxytocin in patients with functional motor symptoms: an open label case series
Objective: Aim of this case series was to assess the effect of a single dose of intranasal oxytocin in a sample of patients with FMS…rTMS-induced effects on Functional Tremor: a randomized, double-blind, controlled study
Objective: To compare the effect on functional tremor (FT) of real rTMS vs sham and to test if hypnosis combined with rTMS might help to…The role of genetic modifiers in Parkinson’s disease-associated LRRK2-G2019S mutation
Objective: The aim of the study is to use genome-wide approach to elucidate genetic variability that influences LRRK2 G2019S penetrance in Parkinson's Disease (PD). Background:…Association analysis between SCNN1A rs10849446, SPTLC3 rs6041636 and rs627354 and Parkinson’s disease and multiple system atrophy in a large Chinese population
Objective: Considering the overlap in clinical manifestations, genetic findings and pathological hallmark between PD and MSA, we aimed to study the association between these 3…Parkinson’s disease Polygenic Risk Factor Scores in Patients with Inflammatory Bowel Disease
Objective: To assess the genetic risk factors for Parkinson’s disease (PD) in a large population of patients with inflammatory bowel disease (IBD), as compared to…SNP assessment and gene expression analysis of alpha-synuclein (SNCA), LRRK2 gene and parkin (PRKN) gene in chewing tobacco exposures and find out the risk of Parkinson’s disease
Objective: We aimed to find out the molecular assessment of the risk of Parkinson’s disease (PD) in tobacco exposure through the SNP and gene expression…
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