Natural History of Movement Abnormalities on Hereditary Spastic Paraplegia: validation of timed functional instruments
Objective: To evaluate the natural history of Hereditary Spastic Paraplegia (HSPs) and to define sensitivity to change, minimal clinically important difference (MCID) and validity of…The Impact of the New Classification Criteria on the Incidence of Tremor Syndromes
Objective: To compare the incidence of the different tremor syndromes using 1998 versus 2018 consensus criteria for classifying tremor disorders. Background: In 1998, the Consensus…Prevalence and Patterns of Rest and Action Tremor in Drug-naïve Parkinson’s Disease
Objective: We aimed to describe the prevalence and patterns of rest and action tremor in a large, prospective cohort of Parkinson’s disease (PD) patients. Background:…GluRδ2 protein reduction in cerebellar Purkinje cells contributes to the pathogenesis of essential tremor
Objective: To identify a molecular substrate reflecting kinetic tremor, the core feature of essential tremor (ET) Background: ET is one of the most common movement…Dystonic versus parkinsonian tremor
Objective: To present cases of patients with diagnostic uncertainty between tremor in Parkinson’s disease (PD) and dystonic tremor. Background: Some patients with clinical presentation of…Memantine induced dyskinesia in Alzheimer’s disease
Objective: There is only little evidence for memantine induced dyskinesia in Alzheimer’s disease. We present a patient with Alzheimer’s disease who developed choreatic dyskinesia as a result…Smartphone-based gait assessment of psychiatric patients on neuroleptics
Objective: To characterize gait performance recorded from psychiatric patients on neuroleptics (PPN) and to compare it to Parkinson’s disease (PD) patients and healthy controls (HC).…Fatigue in Parkinson’s disease and its relation with disease duration and treatment
Objective: Identify the presence of fatigue in a population of PD patients, establishing its association with disease duration and treatment. Background: Fatigue is one of…Auditory processing in young patients of Essential Tremor
Objective: The study aims at exploring auditory aspects in young patients with Essential Tremor. Background: Patients with Essential tremor (ET) manifest with motor as well…Glycopyrrolate as inhalation for treating sialorrhea in Parkinson’s Disease
Objective: To evaluate the safety, tolerability and effect of glycopyrrolate inhalations in PD patients with sialorrhea. Background: Sialorrhea is reported in up to 60 percent…
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