MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Multimodal EEG-MRI based machine learning model in identifying Parkinson’s disease with mild cognitive impairment

    J.H Zhang, L.J Wang, K. Nie (Guangzhou, China)

    Objective: To evaluate the diagnostic value of quantitative electroencephalogram (qEEG) and structure Magnetic resonance (sMR) in identifying mild cognitive impairment in Parkinson’s disease (PD-MCI) via…
  • MDS Virtual Congress 2020

    Moderately frequent and private variants in PRKN are associated with late-onset Parkinson’s disease

    F. Hopfner, S.M Müller, SS. Szymczak, O. Junge, L. Tittmann, S. May, K. Lohmann, G. Grallert, B. Schormair, J. Winkelmann, B. Mollenhauer, C. Trenkwalder, W. Maetzler, D. Berg, M. Kasten, C. Klein, G. Hoeglinger, T. Gasser, G. Deuschl, A. Franke, M. Krawczak, A. Dempfle, G. Kuhlenbäumer (Hannover, Germany)

    Objective: We hypothesized that heterozygosity for rare coding variants in PRKN, PINK1 or PARK7 might also represent a risk factor for sporadic late-onset PD.[4] Background:…
  • MDS Virtual Congress 2020

    Association of Interleukin (IL)-2 and IL2RA gene polymorphisms with Parkinson’s disease in Taiwan

    T. Liu, Y. Wu, Y. Chen, H. Fung, C. Chen (Taoyuan, Taiwan)

    Objective: The purpose of this study is to investigate if interleukin 2 (IL-2) and interleukin 2 receptor alpha (IL2RA) genes are associated with Parkinson’s disease…
  • MDS Virtual Congress 2020

    Educating Spanish-Speaking Communities about Parkinson’s, Research Participation and Genetics: A Community Health Worker (Promotores) Model For Outreach

    K. Schroeder, S. Osborne, D. Sperlakis, E. Mackenzie, I. Mata, C. Martinez (New York, NY, USA)

    Objective: To prepare promotores to educate Spanish-speaking communities about Parkinson’s disease (PD), research participation and genetics. Background: Hispanic PD communities are less likely to see a specialist and are underrepresented…
  • MDS Virtual Congress 2020

    Association between ZNF184 and symptoms of Parkinson’s disease in southern Chinese

    B.Z Zhang, G.L Li (shanghai, China)

    Objective: The aim was to investigate the association between ZNF184 and symptoms of Parkinson’s disease (PD) in southern Chinese. Background: Parkinson’s disease (PD) is a…
  • MDS Virtual Congress 2020

    The role of peripheral T- and B-lymphocytes in LRRK2-mediated Parkinson’s disease

    E. Kozina, M. Byrne, L. Oakley, R. Smeyne (Philadelphia, PA, USA)

    Objective: To test the hypothesis the neurodegenerative cascade in the CNS that leads to Parkinson’s disease (PD) is initiated by signals emanating from the peripheral…
  • MDS Virtual Congress 2020

    Clinical and Genetic Characteristics of the University of Pennsylvania Parkinson’s Disease Population: Results from the Molecular Integration in Neurological Diagnosis (MIND) Initiative

    T. Tropea, N. Amari, N. Han, E. Suh, V. Van Deerlin, A. Chen-Plotkin (Philadephia, PA, USA)

    Objective: To describe the clinical characteristics and the frequency of GBA and LRRK2 variants in the Parkinson’s disease (PD) patient population at The University of…
  • MDS Virtual Congress 2020

    Non-motor network decoupling accompanies conversion to freezing of gait in Parkinson’s disease

    N. D'Cruz, S. Chalavi, M. Gilat, A. Nieuwboer (Leuven, Belgium)

    Objective: To investigate the resting state connectivity in cortico-striatal-thalamo-cortical networks pre-conversion and pre- to post-conversion to Freezing of Gait in Parkinson’s disease. Background: Freezing of…
  • MDS Virtual Congress 2020

    Elevated nigral iron is associated with low plasma serotonin in Parkinson’s disease

    L. Jellen, A. Snyder, G. Du, M. Lewis, E. Wang, C. Capan, P. Brundin, L. Brundin, J. Connor, X. Huang (Hershey, PA, USA)

    Objective: The objective of this work was to determine whether plasma serotonin levels in Parkinson’s disease (PD) are related to iron levels in the brain,…
  • MDS Virtual Congress 2020

    Graph theory analysis of dopamine D2 receptor network in Parkinson’s disease patients

    A. Mihaescu, J. Kim, S. Cho, M. Diez-Cirarda, M. Valli, Y. Koshimori, A. Strafella (Toronto, ON, Canada)

    Objective: The aim of this study was to explore a novel method of analyzing positron emission tomography (PET) data using graph theory analysis. To this…
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