Cardiac Autonomic Dysfunction in Patients with Multiple System Atrophy: A cross-sectional study
Objective: The study aimed to assess cardiac autonomic dysfunction in patients with multiple system atrophy (MSA). Background: MSA is a progressive neurodegenerative disorder with predominant…Cardiac Safety of PBT434, an Inhibitor of Alpha-Synuclein Aggregation for the Treatment of Multiple System Atrophy (MSA)
Objective: Evaluate potential cardiac liability of PBT434 using concentration-response and outlier analyses of ECG and pharmacokinetic (PK) data from a Phase 1 study of PBT434…The severity and distribution of tau pathology distinguish corticobasal degeneration and progressive supranuclear palsy
Objective: To elucidate whether the severity and distribution of tau pathology reflect the clinical presentations in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Background:…Parkinsonism, delayed chorea and dystonia caused by extrapontine myelinolysis
Objective: To describe two case reports of patients with movement disorders due to extrapontine myelinolysis. Background: Central Pontine Myelinolysis (CPM) and Extra pontine myelinolysis (EPM)…Parkinsonism secondary to mercury poisoning in a Colombian population
Objective: To describe the clinical and paraclinical characteristics of patients over 18 years of age who consulted the Neurology service of the University Hospital with…Phenotyping spasticity-associated tonic spasms: implications for therapy
Objective: To evaluate common phenotypes of tonic spasms (TS) in patients with spasticity and inform therapeutic interventions. Background: Spasticity can be associated with several hyperkinetic…Cranial functional movement disorders: Clinical features, associated conditions and precipitating factors
Objective: We aimed to examine our large series of functional movement disorder (FMD) patients where the cranial muscles were involved in order to determine their…Experiences of people with Parkinson’s disease exercising at a centre and at home
Objective: To explore the experiences of people with Parkinson’s disease (PD) of exercising in a predominantly centre-based physiotherapy program and a remotely-monitored home-based program. Background:…The Benchmark Clinic: A Comprehensive Care Model for People with Parkinson’s Disease
Objective: To determine whether an interdisciplinary one-stop care model improves (1) patient engagement and (2) patient outcomes for people with Parkinson's disease (PwP). Background: PwP…Implementation of computer game technologies for patients with ataxia due to post-traumatic head injury: Randomized controlled trial
Objective: Up to 85 % of patients with post-traumatic brain injury suffer motor discoordination, ataxia and dyspraxia. The formation of the correct movement patterns, improved…
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