Changes in the AKT/GSK3 pathway in the cerebellum increase susceptibility to movement disorders in a rat model of post-traumatic stress disorder
Objective: In an effort to investigate the role of PTSD in the aetiology of movement disorders, we assessed changes related to PTSD using the neurotrophic…Psychometric properties of clinical indicators of device-aided therapy eligibility among Parkinson’s disease patients: Real-world data from 6 countries
Objective: Evaluate the performance of clinical indicators for Device-aided Therapy (DAT) eligibility in real-world setting. Background: Timely initiation of appropriate DAT may improve quality of…Speech biometrics can predict cerebellar dysfunction in multiple sclerosis
Objective: To objectively describe cerebellar mediated speech function using a multiparameter index that reflects pathology and quality of life in MS. Background: Cerebellar function plays…Allied health interventions for freezing of gait in Parkinson’s disease: a protocol for a systematic review and meta-analyses
Objective: The primary aim is to determine whether allied health interventions reduce freezing of gait (FOG) in people with Parkinson’s disease (PD) in the short-term…Respiratory training in Parkinson’s disease: a systematic review
Objective: This systematic review provides an overview investigating the effects of different respiratory training interventions in Parkinson’s disease (PD). Background: Signs of respiratory dysfunction are…Nutrient patterns in Parkinson’s disease: A case-control study
Objective: The aim of this study is to evaluate dietary habits and food preferences of PD patients versus healthy controls. Background: Currently, there is a…Wilson and Parkinson’s Disease: Beyond Copper Metabolism
Objective: To show an unusual presentation of Wilson´s disease. Background: Parkinsonism is evident in approximately 40% of patients with Wilson’s disease and responds favourably to…Loss‐of‐function mutations in NR4A2 cause dopa‐responsive dystonia-parkinsonism
Objective: To report two patients with early-onset dystonia-parkinsonism as a result of loss-of-function mutations in nuclear receptor subfamily 4 group A member 2 (NR4A2). Background:…Item Response Theory Analysis of the MDS-UPDRS Motor Examination: Tremor vs. Non-tremor Items
Objective: To investigate the dimensionality of MDS-UPRS Motor Examination (Part 3) using Item Response Theory (IRT). Background: In Parkinson's disease (PD), tremor severity behaves differently…Neuronal Inclusion Formation and Axonal Degeneration in Mutant TFG Transgenic Mice
Objective: To investigate the TFG pathology by analyzing transgenic mice expressing mutant TFG protein. Background: It has been demonstrated that missense variants in TFG gene…
