MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Task based profiles of language impairment in Parkinson’s Disease

    A. Lowit, M. Roheger, E. Kalbe, T. Thies, J. Steffen, M. Barbe (Glasgow, United Kingdom)

    Objective: This study aimed to add to our understanding of language impairment in people with Parkinson's Disease (PwPD). Background: Language difficulties are increasingly reported in…
  • MDS Virtual Congress 2020

    Improved verb use in Parkinson’s disease following intensive voice treatment

    A. Ramage, C. Fox, A. Halpern, L. Ramig (Durham, NH, USA)

    Objective: To identify changes in language production secondary to voice treatment in speakers with Parkinson’s disease (PD). Background: ​Given the role of voice in language…
  • MDS Virtual Congress 2020

    Vascular, inflammatory and metabolic risk factors in relation to dementia in Parkinson’s disease patients with type 2 diabetes mellitus

    Q. Wang (Guangzhou, China)

    Objective: Identifying the risk factors of dementia in patients with both Parkinson’s disease (PD) and type 2 diabetes mellitus (DM) (PD-DM) is clinically relevant and…
  • MDS Virtual Congress 2020

    The ADNPC-RS: a risk score that identifies Lewy body disease individuals at risk for developing concomitant Alzheimer’s pathology

    D. Dai, T. Tropea, J. Robinson, E. Suh, H. Hurtig, D. Weintraub, V. Van Deerlin, E. Lee, J. Trojanowski, A. Chen-Plotkin (Philadelphia, PA, USA)

    Objective: To identify which common genetic variants that confer risk for Alzheimer’s disease (AD) also predict the development of concomitant AD pathology in patients with…
  • MDS Virtual Congress 2020

    Survival in Parkinson’s Disease and Association with MAPT and APOE

    S. Kola, S. Armasu, D. Weis, O. Ross, D. Maraganore, A. Hassan (Rochester, MN, USA)

    Objective: To assess survival in a large cohort of Parkinson's disease (PD) patients, and to determine if survival correlates with MAPT and APOE gene variants.…
  • MDS Virtual Congress 2020

    Human induced pluripotent stem cells (iPSCs) as a model for the study of neural development in Parkinson’s Disease patients carrying GBA mutations

    F. Motolese, A. Casamassa, A. Vescovi, V. Di Lazzaro, J. Rosati, M. Marano (Rome, Italy)

    Objective: The aim of this study is to evaluate in vitro development of human induced pluripotent stem cells (iPSCs) [1] derived from fibroblasts of Parkinson’s…
  • MDS Virtual Congress 2020

    Characterizing Global Cohorts with Monogenic Parkinson’s Disease

    E.J Vollstedt, S. Schaake, M. Kasten, K. Lohmann, C. Klein (Lübeck, Germany)

    Objective: To clinically and genetically characterize a global sample of subjects with monogenic Parkinson’s disease (mPD) and unaffected mutation carriers. Background: Publications on patients with…
  • MDS Virtual Congress 2020

    Auxilin knockout mice: a model for Parkinsonism with dopamine dysregulation and synucleinopathy

    V. DJ, S. Chandra (New Haven, CT, USA)

    Objective: To evaluate the role of auxilin in the pathogenesis of Parkinson’s disease (PD). Background: Auxilin or DNAJC6, a brain-specific co-chaperone plays central role in…
  • MDS Virtual Congress 2020

    Is it time to consider circulating microRNAs as a diagnostic biomarker in REM sleep behavior disorder?

    C. Peralta, D. Giardino, A. Garay, J. Fededa, S. Valiensi, V. Barrachina (Buenos Aires, Argentina)

    Objective: To detect the expression of two circulating microRNAs (miRNAs) in patients with REM sleep behavior disorder (RBD) compared to patients with Parkinson´s Disease (PD).…
  • MDS Virtual Congress 2020

    Spatiotemporal Changes in Substantia Nigra Neuromelanin Content from Prodromal to Clinical Parkinson’s Disease

    E. Biondetti, R. Gaurav, L. Yahia-Cherif, G. Mangone, N. Pyatigorskaya, R. Valabrègue, C. Ewenczyk, M. Hutchison, C. François, J.C Corvol, M. Vidailhet, S. Lehéricy (Paris, France)

    Objective: To investigate the voxel-wise spatiotemporal changes in neuromelanin-sensitive MRI (NM-MRI) signal in the substantia nigra and their relation to clinical scores of disease severity…
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