Investigating Substantia Nigra Damage using Fully Automated Segmentation of Neuromelanin MRI in Early Parkinson’s Disease
Objective: Development of reliable imaging biomarkers of dopaminergic cell neurodegeneration is crucial to facilitate therapeutic drug trials in Parkinson's disease (PD). Neuromelanin-sensitive (NM) MRI techniques…Levodopa improves tremor symptom by reducing the connectivity between the thalamic subregions and postcentral gyrus in patients with Parkinson’s disease
Objective: To explore the mechanism by which levodopa modulates the functional connectivity of the subregions of the thalamus and which subregional connectivity changes are associated…Thalamic nuclei volumes and intrinsic thalamic network in motor subtype in Parkinson’s disease
Objective: The aim of this study is to investigate the alterations of thalamic nuclei volumes and intrinsic thalamic network in patients with de-novo PD according…Altered metabolic and functional resting state activity in cognitively unimpaired and impaired Parkinson’s disease patients
Objective: To assess the correspondence between functional connectivity and metabolic covariance in healthy controls and Parkinson’s disease patients (PD) with and without cognitive impairment. Background:…Diffusion Magnetic Resonance Imaging with Neurite Orientation and Dispersion Imaging (NODDI) Detects Early Localized Cortex Disruption in Parkinson’s Disease
Objective: To use diffusion kurtosis MRI with NODDI to assess brain cortex microstructure in Parkinson’s patients and localize disease related changes. Background: Cortical atrophy has…Predicting Longitudinal Atrophy in Parkinson’s Disease using SIR model
Objective: To predict longitudinal brain changes in Parkinson's disease (PD) using an agent-based model. Background: Considerable evidence suggests that α-synuclein(α-syn) behaves in a prion-like fashion,…An overview of vestibular function in Parkinson’s disease
Objective: To determine if people with Parkinson’s disease (PD) have greater vestibular dysfunction than age-matched healthy people (HC). Background: The vestibular system is crucial for…Analysis of pupillometer results according to motor symptoms severity in Parkinson’s disease patients
Objective: To investigate the value of pupillometric parameters according to the progress of Parkinson’s disease (PD). Background: Pupil light reflex is known to be associated…Quantitative Autonomic Testing in Parkinson’s Disease
Objective: This study was done to find the clinical correlates with quantitative autonomic testing in Parkinson's disease. Background: Autonomic dysfunction is common and causes variety…Sex-associated difference in the presentation and progression of Parkinson’s disease
Objective: Identifying the contribution of sex to the heterogeneity in presentation and progression of Parkinson’s disease (PD). Background: The different prevalence of Parkinson’s disease (PD)…
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