Speech is a sensitive marker in premanifest Huntington’s disease: exploring acoustic, cognitive and fine motor performance
Objective: To explore the utility of objective analysis of speech as a quantifiable clinical biomarker in premanifest HD. Background: The autosomal dominant inheritance of Huntington’s…A Rare Disease with Atypical Clinical And Imaging Findings: Anti Lgi-1 Encephalitis
Objective: We present a case that will raise awareness about the disease with atypical clinical and rich imaging findings that has benefited greatly from intensive…Perillyl alcohol restores mitochondrial dysfunction and abridge NLRP3 inflammasomes activation in in-vitro and in-vivo model of Parkinson’s disease
Objective: Parkinson's disease (PD) affects around 2-3% population of age greater than 65 and is the second most common neurogenerative disorder. The molecular mechanism underpinning…Validation of MDS-UPDRS-based score to predict conversion to freezing of gait in Parkinson’s disease
Objective: To validate an MDS-UPDRS component score for predicting conversion to freezing of gait in Parkinson’s disease. Background: Freezing of gait (FOG) is a debilitating…Treatment of hemichorea-hemiballism with valbenazine
Objective: To describe a video-case report of hemichorea-hemiballism improved by valbenazine therapy Background: Hemichorea-hemiballism (HCHB) is an uncommon movement disorder with numerous etiologies including structural…Real-World Healthcare Resource Utilization in Patients with Parkinson’s Disease and Motor Fluctuations
Objective: To evaluate healthcare resource utilization (HCRU) patterns in patients with Parkinson’s disease (PD) and motor fluctuations (MF) with carbidopa/levodopa (CD/LD) and other adjunctive PD…Trends and Racial Disparities of Palliative Care Use among Hospitalized Patients with Parkinson’s Disease
Objective: To analyze the rate of palliative care consultations among hospitalized patients with Parkinson’s Disease (PD) using the National Inpatient Sample data from 2007 to…Discrimination of alpha-synuclein strains and sub-strains in Synucleinopathies
Objective: To differentiate and characterize alpha-synuclein strains and sub-strains associated with synucleinopathies. Background: Synucleinopathies are a diverse group of neurodegenerative diseases characterized by misfolding aggregation…Parkinson’s disease patients at Hoehn and Yahr stage 1 show deficits in reactive but not proactive inhibitory control
Objective: We wanted to assess whether i) Parkinson’s disease (PD) patients at Hoehn and Yahr (HY) stage 1 show a global or a selective impairment…Baseline Predictors of Constipation and Probable Rapid Eye Movement Sleep Behavior Disorder (pRBD) for Cognitive Impairment After 5 Years of Parkinson’s Disease (PD) Diagnosis in the Parkinson’s Progression Markers Initiative Cohort (PPMI)
Objective: Cognitive impairment is linked to morbidity and mortality in patients with PD, this study aims to investigate whether the presence of constipation and RBD…
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