Facial emotion recognition and social behavioral problems in de novo parkinson’s disease patients
Objective: To examine facial emotion recognition (FER) as crucial component of social cognition and its relationship with social-behavioral problems in de novo drug-naïve Parkinson’s disease…Providing Genetic Testing and Genetic Counseling to the Parkinson’s Disease Community: the PD GENEration Pilot Study Experience
Objective: A pilot study was conducted to assess the feasibility of offering widespread genetic testing and counseling to patients with Parkinson’s disease (PD) in the…The lack of association between UQCRC1 and Parkinson’s disease in a southwest Chinese population
Objective: To further investigate the association between ubiquinol-cytochrome c reductase core protein I (UQCRC1) and Parkinson’s disease (PD) among ethnic Chinese from southwest China. Background:…The Global Parkinson’s Genetics Program (GP2) Underrepresented Populations Working Group
Objective: GP2's Underrepresented Populations Working Group (WG) was created for individuals working within underrepresented/underserved populations to join forces to increase global representation and decipher the…Comprehensive analysis of PRKN in a large Parkinson’s Disease cohort identifies causative mutations and validates population scale screening by microarray
Objective: To screen for PRKN mutations at the population scale. Background: PRKN mutations are the most common recessive cause of Parkinson’s disease (PD) and are…Determination of 5-HT3 receptor levels with [3H]-GR 65630 binding in hemi-parkinsonian rats with L-DOPA induced dyskinesia
Objective: To determine the distribution of serotonin type 3 (5-HT3) receptors in brain areas implicated in L-3,4-dihydroxyphenylalanine (L-DOPA) induced dyskinesia in the 6-hydroxydopamine (6-OHDA)-lesioned rat…Biomarker candidates – Peptides identified to be differentially abundant in cerebrospinal fluid of patients with Parkinson´s disease
Objective: The aim of this study was to identify cerebrospinal fluid peptides that are differential in the cerebrospinal fluid of patients with Parkinson´s disease. Those…A direct longitudinal comparison of free water diffusion MRI and DaTscan SPECT in Parkinson’s Disease.
Objective: To compare the within-subject longitudinal sensitivity of PD biomarkers derived from DaTscan and Diffusion MRI. Background: Parkinson’s Disease (PD) is associated with impaired striatal…In-vivo cholinergic basal forebrain degeneration and cognition in Parkinson’s disease: imaging results from the COPPADIS study
Objective: To assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in a well-characterized multicentric cohort of Parkinson’s disease (PD)…Sexual divergencies in monoaminergic projections in Parkinson’s disease: a 123I-FP-CIT SPECT study
Objective: To investigate sex differences in nigrostriatal and extrastriatal 123I-FP-CIT SPECT monoaminergic projections in healthy subjects and Parkinson’s disease (PD) Background: preclinical and clinical studies suggest…
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