Parkinson’s disease symptom asymmetry at disease onset corresponds to low-beta power asymmetry in the subthalamic nucleus
Objective: Compare beta-power in the subthalamic nucleus (STN) between the most affected and least affected body side at disease onset. Background: Exaggerated beta activity (13–35…Cholinergic Nucleus 4 Degeneration and Cognitive Impairment in REM Sleep Behavior Disorder
Objective: To determine if there is evidence of cholinergic basal forebrain degeneration, i.e., reduced cholinergic nucleus 4 (Ch4) volume on MRI, in patients with REM…Therapeutic potential of luteolin in manganese induced Parkinson’s disease: Targeting neuroinflammation and oxidative stress.
Objective: To investigate the neurodegenerative facets of Manganese (Mn) in rat model in rat model of Parkinson's disease.To study the neuroprotective effect of luteolin in…Transcranial static magnetic field stimulation of the primary motor cortex in essential tremor
Objective: To test the acute therapeutic effects of transcranial static magnetic field stimulation (tSMS) of the primary motor cortex in patients with essential tremor. Background:…Pattern of non-motor symptoms in Parkinson’s disease: A prospective observational study
Objective: Assessment of non-motor symptoms of PD in a cohort of patients attending a tertiary care hospital Background: Nonmotor symptoms are highly prevalent in PD…Contemporary study of the difficulties of late diagnostics in patients with Huntington’s disease in Uzbekistan
Objective: To identify the causes that lead to late diagnosis of Huntington's disease. Background: Huntington's disease is a rare, progressive, and fatal autosomal dominant neurodegenerative…Advance Care Planning and Parkinson’s disease: patient knowledge assessment
Objective: Evaluate disease knowledge in patients with Parkinson’s disease in an Advance Care Planning (ACP) clinic. Background: Poor disease knowledge has been associated with misconceptions…Case reports of first experiences worldwide with novel continuous oral levodopa dental pump in Parkinson’s Disease Patients
Objective: To assess the safety, tolerability, and pharmacokinetics (PK) of a novel continuous levodopa-carbidopa oral pump (LCOP) delivery system in patients with early PD. Background:…Endocannabinoid Dysfunction in Human Disease: Neuro-Ocular DAGLA-related Syndrome (NODrS), a unique pediatric condition
Objective: To define a new pediatric movement disorder and conclusively link the endocannabinoid system to human disease. Background: The endocannabinoid system is a highly conserved…Metagenomic exploration of the gut microbiome in a sibling-controlled pilot study of children with Tourette Syndrome
Objective: To detect gut microbial signatures of Tourette syndrome (TS) in the first sibling-controlled investigation of this condition. Background: The contribution of gut microbiome, and…
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