Anatomical Substrates for Motor Subcomponents of Bradykinesia in Parkinson’s Disease after Subthalamic Nucleus Deep Brain Simulation
Objective: To evaluate distinct anatomical substrates modulating motor subcomponents of bradykinesia following Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD). Background: PD…Deep Brain Stimulation in Generalized Dystonia Caused by PRKRA Mutation
Objective: Dystonia is a hyperkinetic movement disorder with a complex pathophysiology. The medical treatment includes pharmacological treatment, including botulinum toxin (BoNT), which is considered the…Evaluation of the association between total electrical energy delivered (TEED) and cognitive function six months after DBS in patients with Parkinson’s disease
Objective: We aimed to investigate the neuropsychological outcome six months after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkison's disease (PD) patients and…Investigating inflammatory mechanisms in iPSC-derived LRRK2 microglia
Objective: To characterize microglial function and inflammatory mechanisms in LRRK2-associated Parkinson’s disease (PD). Background: PD is a neurodegenerative disease affecting primarily dopaminergic neurons of the…Genome-wide association study of Aβ, t-tau and p-tau in CSF in Parkinson’s disease
Objective: To investigate genetic contributions to the Alzheimer’s disease (AD) related cerebrospinal fluid (CSF) biomarkers in the patients with Parkinson’s disease (PD). Background: Aβ, t-tau…An unusual cause of choreoathetosis: PRES and Goodpasture’s Syndrome
Objective: Our aim is to shed light on an usual cause of choreoathetosis in a medically complex case. Background: Goodpasture’s syndrome(GBS) is a rare autoimmune…Clinically interpretable severity estimation of facial expression impairment in Parkinson’s disease
Objective: To develop a scalable and interpretable computer-vision based algorithm to measure the severity of facial impairment in Parkinson’s disease. Background: Neurological disorders frequently manifest…Apomorphine Sublingual Film for OFF Episodes in Parkinson’s Disease: Incremental Motor Improvement Observed with Increasing Doses
Objective: Evaluate magnitude of motor improvement with increasing doses of apomorphine sublingual film (SL-APO) in patients with Parkinson’s disease (PD) and OFF episodes. Background: Identifying…Assessment of mood symptoms and influence on disease in cervical dystonia
Objective: To compare mood symptom rating scales and influence of anxiety and depressive symptoms on motor severity and aspects of quality of life. Background: Cervical…Asymmetry of Motor and Non-motor Signs in Parkinson’s Disease: An Exploratory Clinical Case-control Study
Objective: To identify, quantify and correlate asymmetry between motor and non-motor signs in early Parkinson’s disease (PD). Background: Asymmetry of motor signs in PD reflects…
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