MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2022 International Congress

    Short-latency afferent inhibition for the assessment of cholinergic degeneration in Parkinson’s disease

    E. D'Angremont, I. Zijdewind, S. Vander Zee, E. de Vries, T. van Laar, I. Sommer (Groningen, Netherlands)

    Objective: Our objective is to assess how well short-latency afferent inhibition (SAI) represents cortical cholinergic system integrity in patients with Parkinson’s disease (PD), using cholinergic…
  • 2022 International Congress

    Effects of directional subthalamic deep brain stimulation on gait and balance in Parkinson Disease patients.

    S. Cherif, C. Olivier, J. Bourilhon, D. Bannier, D. Maltête, B. Lau, S. Derrey, E. Bardinet, C. Karachi, M. Welter (Paris, France)

    Objective: To assess the effects of directional STN-DBS on gait and balance in PD patients Background: STN-DBS is efficient to treat motor signs in PD…
  • 2022 International Congress

    APOE effect on Progressive Supranuclear Palsy phenotypes

    Y. Abida, I. Kacem, S. Mrabet, A. Gharbi, A. Souissi, A. Gargouri, A. Nasri, R. Gouider (Mannouba, Tunisia)

    Objective: To assess the influence of the Apolipoprotein E (APOE) gene variants on Progressive supranuclear palsy (PSP) phenotypic expression. Background: PSP is a rare neurodegenerative…
  • 2022 International Congress

    Longitudinal evaluation of hypomimia in individuals with Parkinson’s disease using a video analytics tool

    P. Yang, M. Islam, A. Abdelkader, W. Rahman, M. Pawlik, S. Jensen-Roberts, E. Waddell, T. Myers, J. Soto, E. Hartman, E. Nnadika, R. Wilson, K. Lizarraga, C. Tarolli, R. Schneider, E. Dorsey, J. Adams, E. Hoque (Rochester, USA)

    Objective: To assess hypomimia longitudinally in individuals with Parkinson’s disease (PD) using a video analytics tool. Background: Recent advancements in video analytics - the use…
  • 2022 International Congress

    Screening of autistic traits in people with functional neurological disorders

    B. Gonzalez-Herrero, F. Morgante, J. Pagonabarraga, B. Stanton, M. Edwards (London, United Kingdom)

    Objective: To examine self-reported autistic traits in people with functional neurological disorders (FND) and the prevalence of diagnosed autism spectrum disorders (ASD) among people with…
  • 2022 International Congress

    Designing a multi-arm multi-stage trial for Parkinson’s

    M-L. Zeissler, M. Burnell, T. Barber, Y. Ben-Shlomo, R. Chapman, C. Clarke, C. Counsell, M. Edwards, R. Ellis-Doyle, C. Gonzales-Robles, A. Jewell, G. Mills, J. Rudiger, D. Salathiel, S. Whipps, A. Whone, T. Foltynie, C. Carroll, R. Barker, J. Carpenter (Plymouth, United Kingdom)

    Objective: The Edmond J Safra ACT-PD initiative (EJS ACT-PD) is developing the first multi-arm multi-stage (MAMS) platform trial for potential disease modifying approaches for Parkinson’s…
  • 2022 International Congress

    Examining the sex differences in the prevalence and incidence of Parkinson disease

    A. Zirra, S. Rao, J. Bestwick, R. Rajalingam, C. Marras, C. Blauwendraat, I. Mata, A. Noyce (London, United Kingdom)

    Objective: The objective of this meta-analysis was to examine the male-to-female (M/F) incidence and prevalence of Parkinson disease. Background: Parkinson disease (PD) is a major…
  • 2022 International Congress

    Multimodal mechanistic disease stratification in sporadic Parkinson’s disease

    T. Payne, T. Burgess, M. Sassani, S. Roscoe, S. Bradley, A. Anton, E. Reed, I. Wilkinson, H. Mortiboys, T. Jenkins, O. Bandmann (Sheffield, United Kingdom)

    Objective: To mechanistically stratify Parkinson’s disease (PD), applying a combination of putaminal 31Phosphorus magnetic resonance spectroscopy (31P-MRS) with detailed assessment of mitochondrial and lysosomal function…
  • 2022 International Congress

    Resting state functional brain networks associated with emotion processing in frontotemporal lobar degeneration

    F. Agosta, E. Canu, D. Calderaro, V. Castelnovo, S. Basaia, MA. Magno, N. Riva, G. Magnani, F. Caso, P. Caroppo, S. Prioni, C. Villa, D. Pain, G. Mora, L. Tremolizzo, I. Appollonio, B. Poletti, V. Silani, M. Filippi (Milano, Italy)

    Objective: This study investigated the relationship between emotion processing and resting-state functional connectivity (rs-FC) of the brain networks in frontotemporal lobar degeneration (FTLD). Background: Defective…
  • 2022 International Congress

    KMT2B episignature analysis identifies a probably hypomorphic missense variant in a family with dystonic and non-dystonic phenotypes

    S. Siegert, W. Schmidt, M. Freilinger, J. Winkelmann, N. Mirza-Schreiber, K. Oexle, M. Zech (Vienna, Austria)

    Objective: Recently, DNA methylation episignature analysis has been introduced as a tool enabling re-classification of “variants of uncertain significance“ (VUS) in lysine-specific methyltransferase 2B (KMT2B),…
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