The use of artificial intelligence-based chatbot in Parkinson’s disease
Objective: This study aimed to assess the feasibility and efficacy of using an artificial intelligence-based chatbot for smile and speech in Parkinson’s disease (PD). Further,…Multidimensional phenotyping of human stem cell-derived midbrain dopaminergic neurons from a SNCA triplication carrier for drug screening applications
Objective: We hypothesized that combining multiple Parkinson's disease (PD) relevant cellular phenotypes will increase the accuracy, stability, and usability of human midbrain dopaminergic (mDA) neuronal…Effect of freezing of gait and antiparkinsonian medication on joint kinematics and kinetics in gait in patients with Parkinson’s disease
Objective: This study aims to evaluate the interaction between FoG and antiparkinsonian medication on individuals with PD's kinematic and kinetic gait parameters. Background: Regarding Parkinson's…Complications in Patients with Progressive Supranuclear Palsy
Objective: This study elucidated the incidence and features of complications in patients with progressive supranuclear palsy (PSP). Background: PSP is a progressive neurodegenerative disorder accompanied…Acute polyneuropathy in patients with Parkinson’s disease treated with LCIG
Objective: The aim of the study was to determine whether the daily dose of levodopa equivalent daily dose (LEDD) before and after starting levodopa/carbidopa intestinal…Identification and functional characterization of genetic modifier of penetrance in G2019S LRRK2-associated Parkinson’s disease through family whole genome sequencing
Objective: Trait- or disease-associated genetic variants contribute to substantial variability and penetrance of complex traits and diseases in humans. Several causative genes and risk factors…Monitoring local field potentials recorded after implant surgery from deep brain stimulation leads in the subthalamic nucleus using a sheep animal model
Objective: The objective of this study was to track if/how local field potentials (LFP) change characteristics over the first few days after implantation of a…Real-World Deep Brain Stimulation Outcomes Using DBS Systems with Directionality and Multiple Independent Current Control
Objective: We report clinical outcomes associated with the use of Deep Brain Stimulation (DBS) systems capable of directionality and Multiple Independent Current Control (MICC). Background:…Environmental factors and Parkinson’s disease
Objective: To assess environmental factors in the development and protection of Parkinson's disease. Background: The cause of Parkinson's disease is not known, but in summarizing…Intraoperative quantification of MDS-UPDRS tremor measurements using 3D accelerometry
Objective: This study focuses on translating parkinsonian tremor tests to an objective method to rate tremor severity using 3D accelerometry, that can be used during…
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