Systematic Review and Network Meta-Analysis of COMT and MAO-B Inhibitors in Parkinson’s Patients with Motor Fluctuations
Objective: This study compared the effects of catechol-O-methyl transferase (COMT) inhibitors and monoamine oxidase‑B (MAO-B) inhibitors on mean change from baseline to end-of-study in OFF-time…An Ecologic Study of Aqueous Lead Exposure and Parkinson’s Disease
Objective: Examine the potential role of lead in water as a risk factor for PD. Background: Studying disease rates in different locations is an established…TWO-YEAR LONGITUDINAL FOLLOW-UP OF VISUAL ILLUSIONS AND HALLUCINATIONS IN PARKINSON’S DISEASE
Objective: To determine whether visual illusions (VI) evolve towards visual hallucinations (VH) along the time in Parkinson’s disease (PD), and whether ophthalmological treatment may have…Characterising Natural Killer cells in early Parkinson’s disease
Objective: To determine whether the number and phenotype of Natural Killer (NK) cells in the blood is altered in early Parkinson’s disease (PD). Background: Accumulating…Lymphocyte count/neutrophil-to-lymphocyte ratio and mild cognitive impairment in Parkinson’s disease
Objective: The present study aimed to elucidate whether i) lymphocyte count and neutrophil-to-lymphocyte ratio (NLR) can discriminate Parkinson's disease (PD) patients from healthy controls (HC);…Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson’s disease: the PD COMM randomised controlled trial.
Objective: To evaluate the clinical effectiveness of two speech and language therapy (SLT) approaches compared to no SLT (control) for people with Parkinson’s disease (PD).…A Novel Mutation of GCH1 Gene in a Case of Dopa-responsive Dystonia with Oculogyric Crises
Objective: To report a patient with a novel mutation of GCH1 gene presenting as dopa-responsive dystonia (DRD), parkinsonism, and oculogyric crises (OGC) Background: Autosomal dominant…A bitter syndrome as a cause of refractory movement disorders
Objective: Submit a case of GLUT-1 deficiency for consideration in the differential diagnosis of movement disorders and refractory epilepsies because early treatment will prevent progressive…Effect of exercise on brain metabolism and energetics in PD
Objective: To identity the effect of exercise on brain metabolism and energetics in PD using PET/MR imaging. Background: Aerobic exercise slows PD progression as reflected…Freezing of Gait Can Predict Cognitive Decline in Parkinson’s Disease
Objective: To investigate the associations between cognitive impairment and cognitive decline in different domains and FOG status using multiple neuropsychological tests. Background: Freezing of gait…
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