MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2022 International Congress

    Adult-onset Alexander’s disease – New causal mutation in GFAP gene

    T. Goerttler, L. Zanetti, M. Regoni, K. Egger, E. Kellner, C. Deuschl, C. Kleinschnitz, J. Sassone, S. Klebe (Essen, Germany)

    Objective: In the present study we describe a new mutation (p.L58P) in the GFAP gene and its functional consequences causing a phenotype with adult-onset Alexander’s…
  • 2022 International Congress

    Identifying meaningful symptoms and impacts of disease for patients with early Parkinson’s disease

    J. Mammen, R. Speck, R. Dorsey, M. Müller, P. Yang, S. Jensen-Roberts, M. Kostrzebski, J. Cosman, J. Hellsten, J. Crawford, G. Stebbins, J. Cedarbaum, T. Simuni, T. Dam, K. Ward Barowicz, D. Stephenson, J. Adams (Providence, USA)

    Objective: To explore meaningful symptoms and impacts of disease on daily living in individuals with early-stage Parkinson’s disease (PD). Background: Critical Path for Parkinson’s (CPP)…
  • 2022 International Congress

    A systematic review on physical health education interventions for people with Parkinson’s: content, impact and implementation considerations across Parkinson’s trajectory

    L. Alushi, J. Alexander, J. Jones (Cambridge, United Kingdom)

    Objective: To examine the content of education interventions that promote physical activity (PA) behavior in PwP, and to assess their effectiveness on physical and psychosocial…
  • 2022 International Congress

    Demographic and Regional Variation in All-Cause Mortality Rates among United States Medicare Beneficiaries with Parkinson’s Disease

    W. Aamodt, A. Willis, J. Farrar (Philadelphia, USA)

    Objective: To determine whether all-cause mortality rates among persons with Parkinson’s disease (PD) in the United States (US) differ by sex, race/ethnicity, or geographic location.…
  • 2022 International Congress

    Analysis of bilateral subthalamic nucleus deep brain stimulation in patients with monogenic forms of Parkinson’s disease: PRKN and LRRK2

    M. Blázquez Estrada, P. Prendes Fernández, E. Suárez Sanmartín, J. Sol Alvarez, C. García Fernández, J. álvarez Carriles, B. Aragoneses, A. Saiz Ayala, E. Santamarta Liébana, M. Alvarez Martínez (Oviedo, Spain)

    Objective: The aim of this study is to compare the clinical and pharmacological response of bilateral STN DBS in patients with monogenic forms of PD…
  • 2022 International Congress

    Effect of clinical levodopa medication cycle on subthalamic beta band power during therapeutic deep brain stimulation in Parkinson’s disease

    L. Hammer, C. Oehrn, S. Cernera, A. Hahn, M. Shcherbakova, C. Smyth, S. Little, P. Starr (San Francisco, USA)

    Objective: To characterize the effect of levodopa medication cycle on subthalamic nucleus (STN) local field potential (LFP) beta-band power in Parkinson’s disease (PD) in the…
  • 2022 International Congress

    Motor Fluctuations development is associated with non-motor symptoms burden progression in Parkinson´s disease patients. A 2-year follow-up study.

    D. Santos, T. de Deus, C. Cores, M. Feal Painceiras, E. Suárez Castro, C. Martínez, S. Jesús, M. Aguilar, P. Pastor, L. Planellas, M. Cosgaya, J. García Caldentey, N. Caballol, I. Legarda, J. Hernández Vara, I. Cabo, L. López Manzanares, I. González Aramburu, M. Avila, V. Gómez Mayordomo, V. Nogueira, V. Puente, J. Dotor, C. Borrué, B. Solano, M. álvarez Sauco, L. Vela, S. Escalante, E. Cubo, F. Carrillo, J. Martínez Castrillo, P. Sánchez Alonso, M. Alonso Losada, N. López Ariztegui, I. Gastón, J. Kulisevsky, M. Blázquez, M. Seijo, J. Ruíz Martínez, C. Valero, M. Kurtis, O. de Fábregues, J. González, R. Alonso Redondo, C. Ordás, L. López Díaz, D. Mcafee, P. Martínez Martín, P. Mir, C. Coppadis (A Coruña, Spain)

    Objective: The aim of the present study was to analyze the progression of non-motor symptoms (NMS) burden in Parkinson´s disease (PD) patients regarding the development…
  • 2022 International Congress

    Autonomic Nervous System Dysfunction in idiopathic REM sleep behaviour disorder

    Y. Shao, T. Wijratne (Melbourne, Australia)

    Objective: To characterise autonomic impairment in REM sleep behaviour disorders, and to investigate the pathophysiological link between autonomic impairment and REM sleep behaviour disorder Background:…
  • 2022 International Congress

    Longitudinal combined 11C UCB J and 18F FE PE2I PET imaging of presynaptic terminal loss in early Parkinson’s disease.

    A. Delva, K. van Laere, W. Vandenberghe (Leuven, Belgium)

    Objective: To longitudinally assess presynaptic terminal loss in vivo over a 2-year period in people with early Parkinson’s disease (PD). Background: Imaging tools that allow…
  • 2022 International Congress

    Long-Term Neuropsychological Outcomes of Deep Brain Stimulation in Early-Stage Parkinson’s Disease

    M. Hacker, M. Tramontana, J. Meystedt, M. Turchan, K. Harper, B. Eoff, R. Fan, F. Ye, T. Davis, P. Konrad, D. Charles (Nashville, USA)

    Objective: To report long-term (5-year and 11-year) neuropsychological outcomes from the deep brain stimulation (DBS) in early-stage Parkinson’s disease (PD) pilot clinical trial. Background: The…
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