Metoclopramide-induced acute dystonic reaction caused by CYP2D6 *4/*4 and CYP2D6 *10/*10 genotypes
Objective: Objective is to demonstrated the role of CYP P450 2D6 polymorphisms in metoclopramide-induced acute dystonic reactions. Background: Metoclopramide can induce acute extrapyramidal reactions by…Indirect treatment comparison of valbenazine with deutetrabenazine for improvement in total maximal chorea score in Huntington disease
Objective: To conduct an indirect treatment comparison (ITC) between valbenazine and deutetrabenazine using data from clinical trials in adults with chorea associated with Huntington disease…Change in quality of Life, depression, and lived experiences of women with Parkinson’s disease after deep drain stimulation
Objective: This study aimed to investigate the changes in quality of life (QoL), depression and experiences of women with PD implanted with a DBS.This study…Isolated vocal tremor: a case series
Objective: To describe the difficulties and limited treatment options for isolated vocal tremor. Background: Isolated vocal tremor is a unique phenotype of isolated focal tremor…The comparison of curcumin and naringenin effects on motor function in rotenone model of Parkinson’s disease
Objective: The aim of the study was to compare the effects of curcumin and naringenin on rotenone-induced motor deficits and related neurochemical changes. Background: Experimental…LRRK2 kinase activity regulates sphingolipid hydrolase enzymatic activities in different cell lines: induced pluripotent stem cell-derived dopaminergic neurons, primary monocyte‐derived macrophages and SH-SY5Y
Objective: To assess whether inhibition of the kinase activity of LRRK2 affects changes in enzyme activity of sphingolipid hydrolase in the culture of dopaminergic neurons…The induction of mitochondrial damage by alpha synuclein In Parkinson’s disease.
Objective: Alpha synuclein aggregation have been indicted in the process of neuronal cell loss in Parkinson's disease; however, there have been several hypothesis to explain…Increased free water in the putamen in idiopathic REM sleep behaviour disorder
Objective: This study aimed to evaluate the free water in the dorsoposterior putamen of idiopathic REM sleep behaviour disorder (iRBD) patients, which is considered a…Artificial Intelligence to detect and classify tremors in patients with Parkinson’s disease and related conditions
Objective: To develop a machine learning program to detect and classify tremors in patients with Parkinson's disease (PD) and related conditions. Background: PD is the…FRMD5 de novo variants in two cases with childhood onset ataxia and seizures
Objective: To describe two cases affected by childhood onset ataxia and seizures carrying de novo variants in the gene FRMD5 Background: FRMD5 belongs to the…
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