Real-world effectiveness and safety of deutetrabenazine in patients with chorea associated with Huntington disease
Objective: To assess real-world effectiveness and safety of deutetrabenazine (DTBZ) for chorea associated with Huntington disease (HD). Background: Real-world evidence on the impact of DTBZ…Can radiofrequency lesion be better than DBS?
Objective: Pallidotomy represents a viable alternative for Parkinson disease(PD) symptoms treatment and has several important advantages, including a decreased need for access to specialists and clinical follow-up, improved affordability, and a lower infection risk, producing high long-term success rates and low morbidity rates. Background: Pallidotomy is recognized as effective for treating the symptoms of Parkinson's disease. Sometimes, radiofrequency may…Connectomics of Chronic VIM vs Rescue VIM/VO Deep Brain Stimulation in Essential Tremor
Objective: This study aims to use connectomic analysis to determine the difference between fiber pathway activation in patients with ineffective VIM stimulation and effective VIM/VO…Small Molecule Inhibitors for Precise Inhibition of α-Synuclein Oligomer Generation in Parkinson’s Disease (PD)
Objective: To develop small molecule therapeutics for PD that inhibit production of toxic α-synuclein oligomers and reduce aggregate formation, targeting the molecular mechanisms at the…Late Onset Cerebellar Ataxia in a Patient with a Heterozygous Pathogenic KIF1A Mutation: A Case Report
Objective: Expand upon the current phenotypic understanding of those with KIF1A-associated neurological disorder (KAND), including late onset progressive cerebellar ataxia (CA). Background: KAND encompasses a group…Essential tremor and essential tremor plus are essentially similar on electrophysiological tremor analysis
Objective: To analyze and compare the electrophysiological signatures of ET and ET Plus Background: There is an on-going debate about the merits of classifying the…Contactless assessment of rigidity in Parkinson’s disease using machine vision and machine learning
Objective: To develop a contactless assessment model for rigidity evaluation in Parkinson’s Disease (PD) Background: Rigidity in PD is evaluated manually in current practice, and examiners need…Prevalence of depression and cognitive impairment in a Hungarian Parkinson’s disease Center
Objective: Our aim is to determine the prevalence of depression and cognitive impairment (CI) among our PD patients. Background: Depression and CI are the most…Diplopia (Double vision) in Parkinson’s disease patients: prevalence and nonmotor effect
Objective: To assess the prevalence of diplopia in Parkinson’s disease (PD) patients and the correlation of diplopia with visual hallucinations, cognitive dysfunction and motor performance.…Spectrogram helps to differentiate functional tremor from organic
Objective: To describe a possible additional method to differentiate functional tremor (FT) from organic tremor (OT). Background: Functional tremor is the most common manifestation of…
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