Sleep disorders in Parkinson’s disease patients. A case-control study.
Objective: To determine the quality of sleep, the type of sleep disorders and their correlations with motor impairment in Parkinson's disease (PD) patients. Background: Sleep…The effect of exercise training on motor and non-motor symptoms in people with Essential Tremor; a feasibility pilot study
Objective: To examine the potential benefits of an exercise program on motor and non-motor symptoms in people with Essential Tremor (ET) Background: Besides tremor, patients…Caregiver burden in Parkinson disease: an updated scoping review
Objective: We performed a scoping review to describe caregiver burden in Parkinson disease (PD) and build on the evidence provided by Mosely at al. [1]…Very high frequency of early-onset Parkinson’s disease with homozygous PRKN exon 3 deletion amongst indigenous populations in Sabah, Malaysia
Objective: We aimed to investigate the frequency of EOPD and PRKN mutations in our diverse Malaysian indigenous populations, who are extremely under-represented in PD genetics…Transcranial magnetic stimulation study in primary dystonia of presumed genetic etiology
Objective: To study the neurophysiological parameters in primary dystonia of presumed genetic etiology using transcranial magnetic stimulation (TMS) and correlate with their genotype. Background: The…Emerging treatments targeting DNA and RNA in Huntington’s disease: a review of future perspectives and current challenges
Objective: To review the progress made towards the development of a huntingtin (HTT) lowering strategy based on RNA and DNA and also to assess the…Associations between non-motor symptoms and patient characteristics in Parkinson’s disease: A multicenter cross-sectional study
Objective: We aimed to investigate factors associated with non-motor symptoms (NMS) in Parkinson's disease (PD). Background: PD is characterized by a variety of NMS, such…Efficacy of levodopa/carbidopa/entacapone replacement of levodopa/dopa decarboxylase inhibitors in treatment of Chinese Parkinson’s disease patients with wearing-off: a multicenter, randomized controlled, open label study
Objective: This study aimed to investigate the efficacy and safety comparison between LCE and Pramexol in Chinese PD patients with the wearing-off phenomenon. Background: Wearing…Analysis of the therapeutic potential of IkT-148009 in Parkinson’s disease
Objective: To evaluate the therapeutic potential of the selective, brain penetrant c-Abl inhibitor IkT-148009 in mouse models of progressive PD and the safety and tolerability…Validating wearable sensors as an assessment tool for Parkinson’s Disease
Objective: The objective of our pilot study was to assess the feasibility of using a portable accelerometer system to accurately identify motor findings in patients…
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