A Retrospective Review of Amantadine in Progressive Supranuclear Palsy
Objective: To determine the efficacy and tolerability of amantadine in Progressive supranuclear palsy (PSP). Background: PSP is one of the most common atypical parkinsonian disorders,…Gut dysbiosis in Indian Parkinson’s Disease Patients with Constipation
Objective: To analyse the gut microbiome and explore dysbiosis in Indian Parkinson’s Disease patients with and without constipation. Background: Global studies have associated gut dysbiosis…Potential role of Alpha-synuclein levels in Platelets in GBA-related PD
Objective: Identification of a blood biomarker to predict PD diagnosis or to monitor the disease progression. Background: Previous evidence suggests differences in systemic alpha-synuclein levels…The neuroprotective miRNA family hsa-miR-451 has a distinctive pattern of downregulation in neurodegenerative diseases.
Objective: 1.Identification of microRNAs from whole blood PBMCs of SCA2 patients by using NGS. 2.To check the exclusivity of miRNAs in SCA2, SCA1,SCA3,SCA12,HD,ALS,PD and MSA-C…Characterization of haemodynamic activity in resting-state networks associated with cognitive decline in PD: a fractal analysis approach
Objective: To characterize the frequency dependence and the complexity changes of functional connectivity associated with PD cognitive decline. Background: Changes in spontaneous neural activity have…Uncovering the mechanisms of genotype by environment interaction in an idiopathic Parkinson’s disease model in Drosophila
Objective: To identify the genetic basis and the molecular mechanisms that underlie the susceptibility of developing motor defects in response to exposure to pesticides in…APOE-ɛ4 status and cognitive decline after subthalamic nucleus-deep brain stimulation in Parkinson’s disease: preliminary results of the GENEPARK-DBS study
Objective: The aim of this study was to evaluate wheter the presence of APOE-ε4 in a cohort of Parkinson’s disease (PD) patients treated with subthalamic…Novel RAB39B stop mutation in patient with typical Early-Onset Parkinson’s disease
Objective: N/A Background: RAB proteins are small guanosine triphosphatases (GTPases) that are ubiquitous and expressed in all cell types regulating vesicular transport and intracellular membrane…TEP-PSP: preliminary results of a therapeutic education program in progressive supranuclear palsy
Objective: To explore the feasibility and satisfaction of a therapeutic education program (TEP) in progressive supranuclear palsy (PSP). Background: PSP is a rare tauopathy with…Synaptic density and α-synuclein oligomers in skin biopsies: differences between idiopathic and GBA-linked Parkinson’s disease
Objective: To compare α-synuclein oligomers and synaptic density (SD) in skin biopsies from PD and GBA-PD. Background: Previous research [1] reported α-synuclein oligomers within synaptic terminals of autonomic fibers in…
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