Clinical, radiological and genetic spectrum of fifteen cases of PLA2G6-Associated Neurodegeneration – A Single Centre Cohort from India
Objective: To study the clinical, radiological and genetic profile of patients with genetically proven PLA2G6-Associated Neurodegeneration (PLAN). Background: PLAN is a clinically heterogenous genetic disorder…Examining the association between adverse effects of magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy for essential tremor and structural connectivity using probabilistic tractography targets
Objective: We examine the relationship between adverse effects of MRgFUS thalamotomy in essential tremor (ET) patients and the structural connectivity of the ventral intermediate nucleus…Tourettism occurring during gender transition with testosterone therapy
Objective: Past decades have seen an increase in gender dysphoria subjects seeking hormonal treatment1,2. We report motor and vocal tics following testosterone therapy introduction for…Certification for advanced practice providers working in movement disorders expands access to quality expert and specialized care.
Objective: Elevate awareness of impact of a professional certification for APPs in PD & movement disorders (PMD), which increases access specialized care, improving outcomes. Demonstrate certification…Improved Tremor Response to Focused Ultrasound Thalamotomy
Objective: This study sought to determine if, when using four tract tractography (FTT) to target the decussating and non-decussating dentatorubrothalamic tracts (DRTTs), essential tremor (ET)…Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming
Objective: We examined whether levodopa-induced dyskinesia (LID) and axon terminal hypertrophy gradually develop with repeated levodopa treatment in Parkinsonian rats to prove that the hypertrophy…Disease progression in Parkinson‘s disease patients with Mild Cognitive Impairment: 5-year longitudinal study from The Early Parkinson’s disease Longitudinal Singapore (PALS) cohort
Objective: To investigate motor, non-motor and cognition progression in early PD patients with Mild Cognitive Impairment (MCI) and normal cognition over 5 years. Background:…Prognostic impact of frontal-lobe clinical bedside signs in progressive supranuclear palsy
Objective: To identify clinical bedside examination signs indicative of frontal lobe dysfunction with a prognostic value in patients with progressive supranuclear palsy (PSP). Background: The…Quercetin hinders Glial Activation to Alleviate the Cadmium Induced Dopaminergic Alteration via TNFα mediated CAMKIIα/ERK activation
Objective: The present study has therefore been carried out identify neuroprotective role of quercetin in alleviating the cadmium induced dopaminergic dysfunctions via glial mediated deactivation…Spinocerebellar ataxia type 28 presenting as spastic paraparesis
Objective: To describe a patient with spinocerebellar ataxia type 28 (SCA28) presenting with isolated spastic paraparesis. Background: Autosomal dominant (AD) mutations in the ATPase family…
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