Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming
Objective: We examined whether levodopa-induced dyskinesia (LID) and axon terminal hypertrophy gradually develop with repeated levodopa treatment in Parkinsonian rats to prove that the hypertrophy…Disease progression in Parkinson‘s disease patients with Mild Cognitive Impairment: 5-year longitudinal study from The Early Parkinson’s disease Longitudinal Singapore (PALS) cohort
Objective: To investigate motor, non-motor and cognition progression in early PD patients with Mild Cognitive Impairment (MCI) and normal cognition over 5 years. Background:…Prognostic impact of frontal-lobe clinical bedside signs in progressive supranuclear palsy
Objective: To identify clinical bedside examination signs indicative of frontal lobe dysfunction with a prognostic value in patients with progressive supranuclear palsy (PSP). Background: The…Quercetin hinders Glial Activation to Alleviate the Cadmium Induced Dopaminergic Alteration via TNFα mediated CAMKIIα/ERK activation
Objective: The present study has therefore been carried out identify neuroprotective role of quercetin in alleviating the cadmium induced dopaminergic dysfunctions via glial mediated deactivation…Spinocerebellar ataxia type 28 presenting as spastic paraparesis
Objective: To describe a patient with spinocerebellar ataxia type 28 (SCA28) presenting with isolated spastic paraparesis. Background: Autosomal dominant (AD) mutations in the ATPase family…Efficacy and safety of adjunctive oral therapy in Parkinson’s disease with motor complications: a systematic review and network meta-analysis
Objective: To review the evidence and compare the efficacy and safety of catechol-O-methyltransferase inhibitors (COMT-Is), dopamine agonists (DAs) and monoamine-oxidase B inhibitors (MAOB-Is) as adjunctive…Investigating factors contributing to clinical trial recruitment in Parkinson’s Disease within the Black community
Objective: This study aimed to investigate the facilitators and barriers to Parkinson’s disease (PD) research engagement within Black people with PD and Black healthy controls.…Compliance with national and international guidelines in the treatment of non-motor symptoms in late stage Parkinson’s disease
Objective: Against a background of the national and international Parkinson's disease (PD) treatment guidelines, the aim of this study was to investigate to which degree…Is it safe to switch from constant voltage to constant current with a mixed Internal Pulse Generator in deep brain stimulation
Objective: Deep brain stimulation (DBS) is an efficient treatment modality for Parkinson's Disease (PD), essential tremor and dystonia. Differing from the Constant Voltage-(CV)-DBS devices, Constant…Does sex affect worsening of cognitive and IADL functions in PD with and without PD-MCI?
Objective: To define how sex affects worsening of cognition and instrumental activities of daily living (IADLs) in a heterogeneous cohort of people with Parkinson’s disease…
- « Previous Page
- 1
- …
- 163
- 164
- 165
- 166
- 167
- …
- 186
- Next Page »