Association Between Antiepileptic Drugs and Subsequent Parkinson’s Disease in East London
Objective: To investigate the association between antiepileptic drugs (AEDs) prescription and subsequent Parkinson’s disease (PD). Background: Recent observational studies have highlighted an association between epilepsy…Reaching kinematics in patients with Spinocerebellar Ataxia Type 12 using a markerless motion tracking system
Objective: In the current study, we compared the kinematics of planar reaching movements between patients with Spinocerebellar Ataxia Type 12 (SCA12) and healthy control using…Blood NfL can track progression in multiple system atrophy
Objective: To validate the role of NfL for disease progression, severity and subject trial selection in MSA. Neurofilament light (NfL) was explored in this regard though…Neuroprotective properties of arylpiperazine-sulphonamides in an in vitro model of Parkinson’s disease
Objective: To investigate the neuroprotective effects of novel arylpiperazine compounds as measured by viability of SH-SY5Y cells in vitro. Background: Parkinson’s disease (PD) is a…Istradefylline therapy for PD plus oromandibular dystonia
Objective: To clarify the dopaminergic system link between parkinson's disease (PD) and oromadibular dystonias (OMDy) co-occur, and the effect of istradefylline (IST) therapy. Background: OMDy are…Risk Factors for Stimulation-Induced Bradykinesia in Dystonia Patients Treated with Deep Brain Stimulation: A Retrospective Analysis.
Objective: Identification of risk factors for stimulation-induced bradykinesia in GPi-DBS Background: Deep brain stimulation (DBS) is an effective treatment for dystonia, but some patients may…Effectiveness of use of Pictographs on Levodopa packaging to ensure awareness of Levodopa/Carbidopa spacing with meals in patients of Idiopathic Parkinson’s disease.
Objective: Food interferes with gastrointestinal absorption of levodopa which requires spacing with meals. This study aimed to evaluate the effect pictographs on Levodopa packaging Fig 1 on increasing patient…Addition contact with 10 Hz stimulation in the STN may improve stimulation-induced cognitive disturbances
Objective: This case report demonstrates improvement of cognition by adding low-frequency stimulation in the ventral subthalamic nucleus (STN). Background: Deep brain stimulation (DBS) targeting the…Longitudinal association of mild behavioral impairment with cognitive decline in Parkinson’s disease
Objective: To analyze the cross-sectional and longitudinal association between mild behavioral impairment and cognitive impairment in Parkinson’s disease. Background: Cognitive impairment and neuropsychiatric symptoms (NPS)…ParkProReakt Study Protocol – A randomized controlled trial to evaluate a proactive approach to health care in Parkinson’s disease
Objective: To implement and evaluate a novel care model for people with Parkinson’s Disease (PD), based on the following principles: proactive, person-centered, and digital (cf.…
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