Safety profile of pimavanserin therapy in elderly patients with neurodegenerative disease-related neuropsychiatric symptoms: a Phase 3b study
Objective: To evaluate the safety profile of pimavanserin in patients with neuropsychiatric symptoms related to neurodegenerative disease (NDD). Background: Patients with NDD including Parkinson’s disease…Risk and protective factors in Parkinson’s disease: a simultaneous and prospective study with linear and machine learning models
Objective: To identify which risk/protective factors influenced most incident Parkinson's disease (PD) risk in a population of almost 24,000 Italian citizens, using both classical statistical…Potential genetic link between type I diabetes and Parkinson’s disease.
Objective: To examine whether type 1 diabetes (T1D) is genetically or causally associated with Parkinson’s disease (PD). Background: Previous epidemiological and mendelian randomization studies demonstrated…Taking the driver’s seat on Parkinson’s care
Objective: To provide insight into the unique service and support offered by the multidisciplinary health team to address the challenges and dilemmas faced by people…Longitudinal follow-up of pure autonomic failure with cardiac sympathetic denervation: Relevance to the body-first theory of Parkinson’s disease
Objective: In this report, we describe eight patients with PAF with nOH and imaging evidence of cardiac sympathetic denervation by 123I-metaiodobenzylguanidine (123I-MBG) single photon emission…Morphometric assessment of age-associated neuronal changes in the human locus coeruleus
Objective: To delineate the age-related changes in the neuronal size and neuromelanin (NM) intensity in autopsied tissues of human locus coeruleus (LC). Background: Many studies…Is working memory training success in Parkinson’s disease determined by cortical thickness and white matter lesions?
Objective: We aimed to evaluate the influence of cortical thickness (CT) and white matter lesions (WML) on working memory training (WMT) success in cognitively unimpaired…Normative values for the Instrumented Timed Up and Go test in Parkinsonian populations
Objective: This study aims to define normative values for the Instrumented Timed Up and Go test using wearable inertial sensors in people affected by Parkinson’s…Evaluating continuous monitoring in Parkinson’s disease through real-world, device-reported outcomes.
Objective: This work presents an analysis of real-world, device-reported outcomes from patients in Greece, following a 6-month, continuous telemonitoring paradigm for Parkinson's disease. Results show…Incremental Hospitalizations and Associated Costs of Co-existing Dementia in Patients with Parkinson’s Disease Psychosis: An analysis of US Medicare Beneficiaries
Objective: To evaluate incremental hospitalizations and costs among Medicare patients with Parkinson's disease psychosis (PDP) vs. PDP+dementia (PDP+D). Background: Research examining hospitalizations and costs of…
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