Cognitive flexibility associates with atrophy and disrupted connectivity of the cognitive cerebellum in degenerative cerebellar ataxia
Objective: This study was to investigate the features of cognitive flexibility in patients with degenerative cerebellar ataxia, and to identify the pathophysiological correlates of cognitive…LRRK2 G2019S mutation in Multiple System Atrophy, a case report
Objective: Presenting a case of Multiple System Atrophy (MSA) confirmed by skin biopsy with a peculiar genetic profile. Background: MSA is a rare neurodegenerative disorder characterized…Isolation of L1CAM-extracellular vesicles reveals signs of insulin resistance in Parkinson’s disease
Objective: The aim of this study was to test the utility of isolating L1 Cell Adhesion Molecule (L1CAM)-derived extracellular vesicles (EVs) in quantification of glucose…Topography of cholinergic vulnerability correlates of PIGD motor deficits in DLB and PSP: A [18F]-FEOBV PET study
Objective: To understand the relationship between cholinergic vulnerability and Postural Instability and Gait Disturbances (PIGD) motor features in dementia with Lewy bodies (DLB), and progressive…Depression in Parkinson’s disease is associated with subcortical neurodegeneration and increased risk of all-cause mortality and dementia
Objective: To evaluate the temporality, neuroanatomical correlates and prognostic significance of depression in PD using a large population cohort. Background: Depression may be an important…Improvement of nocturia symptoms and associated quality of life in patients with Parkinson’s disease treated with foslevodopa/foscarbidopa: results from 2 phase 3 trials
Objective: To assess nocturia over time and its correlation with quality of life (QoL) in patients with Parkinson’s disease (PD) treated with foslevodopa/foscarbidopa (LDP/CDP). Background:…Instability after MRIg-FUS thalamotomy: why does it appear?
Objective: To know the semiological characteristics and physiopathology of instability after thalamotomy with Magnetic Resonance image guided focused ultrasound thalamotomy (MRIg-FUS). Background: Gait instability is…IncobotulinumtoxinA to treat sialorrhea in Parkinson’s disease: a real-life study: 4-year interim results
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea. Background: Sialorrhea is frequently a…Understanding patient perceptions of advanced Parkinson’s disease (aPD) treatments
Objective: To explore patients’ perceptions of treatment options for aPD and treatment decision considerations. Background: As PD advances, some people with Parkinson’s (PwP) on oral…local field potential differences in stn subregion during performance of a conflict task in humans with parkinson’s disease
Objective: Examine dorsal and ventral STN subregion's roles in motor conflict with intraoperative recordings during the implantation of a DBS device in Parkinson’s disease (PD)…
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