POLR3A-Related Disorders and Response to Deep Brain Stimulation
Objective: To expand on the phenotypic spectrum of POLR3A c.1909+22G>A splice variant and report two patients’ tremor response to deep brain stimulation. Background: Polymerase III…Mobile Brain / Body Imaging in early Parkinson’s Disease: the Twin Brain project
Objective: We aimed to setup a novel Mobile Brain / Body Imaging (MoBI) system and to perform a feasibility study for the future investigations of…Effectiveness of at home, repeated transcranial pulse current stimulation (tPCS) sessions for treatment of neurodegenerative ataxia.
Objective: To investigate whether a 2-week treatment with anodal cerebellar and cathodal spinal transcranial pulse current stimulation (tPCS) can improve symptoms in neurodegenerative ataxia at…Impact of the COVID-19 pandemic on DBS accessibility: a single center experience
Objective: To evaluate the impact of the COVID-19 pandemic on accessibility to deep brain stimulation (DBS) care at a tertiary DBS center Background: Early responses…Expanding the reach of a telehealth psychotherapy hub to advance coordinated depression care for rural veterans with Parkinson’s Disease
Objective: To describe the ongoing implementation and expansion of a telehealth psychotherapy hub to treat depression in rural Veterans with PD. Background: Depression is common…Case Report: Supranuclear Palsy and Increased Intraocular Pressure in Normal Pressure Hydrocephalus
Objective: . Background: Normal pressure hydrocephalus (NPH) is characterized by a triad of symptoms: gait abnormality, urinary incontinence (UI) and cognitive decline. Though clinical findings…Natural history and disease progression biomarkers of multiple system atrophy: the ASPIRE-MSA study
Objective: To evaluate multiple system atrophy (MSA) disease progression on a panel of candidate MSA biomarkers pre-selected for their putative involvement in the pathophysiology of…Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Effects of an online 12-week Tai Chi intervention on gait and postural stability in individuals with Parkinson’s disease
Objective: To examine the effects of an online 12-week biomechanical-based TC intervention on gait and posture in people with Parkinson's disease (PD). Background: Postural instability…The monoamine oxidase-B inhibitor selegiline does not affect 18F-Florzolotau uptake in patients with progressive supranuclear palsy: a longitudinal case series
Objective: In a longitudinal case series of patients with progressive supranuclear palsy (PSP), a chronic challenge with the irreversible MAO-B inhibitor selegiline was used to…
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