Genotype and age at onset drive vermis atrophy in CACNA1A and GAA-FGF14 related ataxias
Objective: To assess cerebellar volumetry using a deep learning method in patients with non-polyglutamine CACNA1A- or GAA-FGF14-related disease. Background: Ion channel dysfunction is a recurring…Multiplex Proteomic Analysis of Lewy Body Dementia Reveals Cerebrospinal Fluid Biomarkers of Disease Pathophysiology and Progression
Objective: To evaluate the performance of a multiplexed proteomic assay in a large multi-center Lewy Body dementia (LBD) cohort. Background: LBD, which comprises Parkinson’s disease…Application of Multi-Camera Videography for Detecting PD-related Gait Deficiencies
Objective: To identify and measure PD-specific gait signals in multi-camera videos for differentiating PD vs control (non-PD), without using specialized equipment (e.g., motion capture). Background:…Towards automated deep brain stimulation programming using neurophysiology and artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…Joint Prediction of Motor and Non-motor Deep Brain Stimulation Outcomes using Quantitative Susceptibility Mapping
Objective: To jointly estimate motor and non-motor outcomes of deep brain stimulation using presurgical quantitative susceptibility maps. Background: Parkinson’s disease (PD) patients with motor complications…Efficacy and Feasibility of Telemedicine-Based Dietary Intervention vs. Outpatient Supervision for Drug-Resistant Multiple System Atrophy in Postmenopausal Women During COVID-19
Objective: This study aimed to evaluate the feasibility, safety, and patient satisfaction of initiating and following up on MAD via telemedicine using the Telegram app,…Effectiveness of Interactive Rhythmic Stimulation on Gait Improvement in Elderly Patients: An R and Python Perspective
Objective: To evaluate the effectiveness of interactive rhythmic stimulation on gait improvement in elderly patients using data-driven insights from R and Python-based analyses. Background: Gait…“PICS”: a Novel Radiological Landmark for Thalamic DBS Interventions
Objective: To assess the feasibility of a bright posterior limb of the internal capsule (pLIC) signal (PICS) in DiMANI images, as a reliable landmark for…Diagnostic yield of Whole-genome sequencing in Genetic Movement disorders
Objective: To assess the breadth of presentations to a tertiary neurogenetics clinic and evaluate the diagnostic yield of whole-genome sequencing (WGS) in genetic movement disorders.…Anti Yo-1 Antibody Syndrome: A Case Study of a Paraneoplastic Syndrome Mimicking Atypical Parkinsonism
Objective: To report the case of a patient with anti Yo-1 antibody syndrome mimicking clinically and radiologically as an atypical parkinsonism. Background: The anti Yo-1…
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