Treatment Of Advanced Parkinson’s With Levodopa–Entacapone–Carbidopa Intestinal Gel – Impact On Dyskinesia
Objective: To evaluate the effect of long-term treatment with levodopa–entacapone–carbidopa intestinal gel (LECIG) infusion on daily time with dyskinesia in people with advanced Parkinson’s disease…Opicapone for OFF Motor Fluctuations in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Trials
Objective: To evaluate the efficacy of opicapone 50 mg in reducing OFF time and improving motor function in Parkinson’s disease (PD) patients with motor fluctuations.…COMT-Inhibitors Clinical Experience In Early Motor Fluctuations. Six Months Analysis Of REONPARK Study
Objective: The REONPARK study aims to evaluate COMT inhibitors (COMTi) effectiveness and tolerability in alleviating motor complications associated with L-dopa treatment in Parkinson’s disease (PD)…Comparative Safety of Different Routes of Apomorphine Administration in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To assess the safety profiles of inhaled, sublingual, and subcutaneous apomorphine in patients with Parkinson’s disease (PD). Background: Apomorphine is a direct-acting D1/D2 agonist…Comparative Efficacy and Safety of Opicapone in Parkinson’s Disease: An Updated Systematic Review and Meta-Analysis
Objective: To evaluate the efficacy and safety of Opicapone drug in patients with Parkinson’s disease (PD) using an updated systematic review and meta-analysis, including newly published randomized controlled trials…Serum based estimations of CFAH, Gelsolin, CNDP1 and DKK3 levels suggest involvement of multiple pathways in pathogenesis of Parkinson’s disease.
Objective: To estimate levels of complement factor H (CFAH), phosphorylated alpha-syn (p- a-syn), gelsolin, carnosine dipeptidase-1 (CNDP1) and DKK3 in serum of Parkinson’s disease (PD) patients…Identification of Metabolomic & Proteomic Panels for Parkinson’s Disease progression Diagnosis
Objective: Identify proteomic and metabolomic biomarkers for Parkinson’s Disease (PD) progression diagnosis using statistical and machine learning (ML) approaches, leveraging data from cerebrospinal fluid (CSF)…Privacy and Personalisation: Predicting Parkinson’s Severity with Federated Learning
Objective: To improve privacy and personalisation for artificial intelligence (AI), this work compared federated learning (FL) to a conventional, centralised system for predicting Movement Disorder…Dried Plasma Spot Cards for Measurement of Neurofilament Light Chain
Objective: Evaluate measurement of neurofilament light chain (NfL) in dried plasma spot cards, and to compare these to measurements using more invasive and in person…Cognitive and Motor Wobbling in Isolated RBD: A Multicentric Study by the International RBD Study Group (IRBDSG)
Objective: To define and characterize clinically fluctuating transition phases from isolated RBD (iRBD) to overt alpha-synucleinopathy. Background: Patients with iRBD often develop motor and non-motor…
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