Tendencies of Non-Motor Symptoms and Short-Term Clinical Predictors in Patients with Parkinson’s Disease
Objective: This study retrospectively investigated whether the occurrence of non-motor symptoms and the decline in cognitive function in patients with Parkinson’s disease (PD) influence fall…Association between cognitive adverse effects of anticholinergic medication and development of long-term dementia in Parkinson’s disease
Objective: To investigate whether cognitive adverse effects occurring immediately after taking anticholinergics are related to the development of long-term dementia and to interpret this from…PINK1 activation improves outcomes in the UQCRC1 models of Parkinson’s disease
Objective: To investigate the role of chronic oxidative phosphorylation (OXPHOS) stress in mitophagy and the therapeutic potential of PINK1 activation in the UQCRC1 models of…Moyamoya Disease and the Risk of Parkinson’s Disease
Objective: We aimed to determine whether the risk of Parkinson’s disease (PD) is increased in patients with Moyamoya disease (MMD) and to identify the potential…Decoding Parkinson’s Progression: Longitudinal Volumetric MRI Biomarkers in Prodromal and Clinical Stages
Objective: This study investigates MRI volumetric analysis via VBM as a biomarker for early PD detection, focusing on structural alterations in deep gray matter regions…Contribution of Dopamine Depletion, Cerebral Perfusion, and Cognition to Gait Dysfunction in Parkinson’s Disease
Objective: To explore the potential contribution of dopamine loss, perfusion deficit, and cognition to spatiotemporal gait parameters in patients with Parkinson's disease (PD). Background: Gait…Sub-grouping of Parkinson’s disease based on thalamic subnuclei volume
Objective: We aimed to categorize Parkinson’s disease (PD) using k-means clustering based on thalamic subnuclei volumes measured by structural magnetic resonance imaging (sMRI). Background: The…Levodopa mediated normalization of cerebello-thalamo-cortical GABA and Glutamate in Parkinson’s disease
Objective: This study aims to evaluate the effect of levodopa on cerebello-thalamo-cortical (CTC) gamma-aminobutyric acid (GABA) and glutamate in patients with Parkinson’s disease (PD) using…Evaluation of swallow tail sign on 1.5 Tesla Magnetic Resonance Imaging in Parkinson´s disease patients in a tertiary hospital
Objective: To evaluate the swallow tail sign in 1.5 Tesla magnetic resonance imaging (MRI) scans of patients diagnosed with Parkinson's disease (PD). Background: Nigrosome-1 appears…The Genetic Landscape of Parkinson’s Disease in African and Admixed Populations: Discovering Population-Specific Risk and Unveiling Etiological Insights
Objective: To perform the largest PD risk genome-wide association study (GWAS) in the African and African admixed populations. Background: Investigating the genetic foundation of Parkinson’s…
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