Synchronized High Frequency Neural Oscillations as a Biomarker for Differentiating the Internal from the External Segment of the Globus Pallidus in Parkinson’s Disease
Objective: To assess whether using high frequency oscillations (HFO; 150-350 Hz) or beta band oscillations (13-30 Hz) can objectively differentiate the external from the internal…Dopamine replacement therapy modulates dopa decarboxylase, prolactin and AOC3 levels in Parkinson’s disease
Objective: Investigate the impact of dopamine replacement therapy (DRT) on the serum and CSF proteome of people with Parkinson’s disease (PwPD). Background: New high-throughput technologies…Paradoxical Association of Kinetics of α-Synuclein Seed Amplification 24-hrs Assay and Clinico-Pathological Markers of Parkinson’s disease
Objective: To investigate the association between baseline α-synuclein seed amplification assay (SAA) parameters and clinical and biomarker features of Parkinson’s disease (PD) at baseline and…Eye movement abnormalities in GBA1-related Parkinson’s disease and non-manifesting GBA1-carriers
Objective: To perform an in-depth characterization of eye movement abnormalities in Parkinson’s disease (PD) and non-manifesting carriers of GBA1 pathogenic variants. Background: Eye movement abnormalities…Salivary Biomarkers in Parkinson’s Disease: A Follow-Up Study
Objective: Investigate longitudinal changes in salivary levels of oligomeric and total a-synuclein (a-syn), phosphorylated-tau (p-tau), total tau, MAP-LC3, and TNFa in Parkinson’s Disease (PD) patientsAssess…Alpha-Synuclein Preformed Fibrils Increase the Frequency of CXCR3+ B-cells in Early-stage Parkinson’s Disease Patients
Objective: To investigate the effect of a-Syn Preformed Fibrils (PFF) on CXCR3 expression on B-cells in Parkinson’s Disease (PD) patients at early (E-PD, diagnosed less…Factors contributing to balance discordance and its impact on fear of falling avoidance behavior in Parkinson’s disease
Objective: To identify cognitive and psychological factors contributing to balance discordance in people with Parkinson's disease (PwPD) and examine how it is associated with fear…GPi Lesioning vs. DBS: Does Targeting the Same Structure Differently Affect Cognition in Parkinson’s Disease?
Objective: To compare the cognitive and quality of life (QoL) outcomes of GPi-DBS and GPi-RF, investigating whether lesion-based approaches pose a greater cognitive burden over…Approaches to understanding the role of STN in the development of ICD in Parkinson’s disease
Objective: The aim of this study was to identify the features of subthalamic tracts in PD patients with ICD. Background: Recurrent negative feedback loops from…Cognitive Decline in Parkinson’s Disease: A Decade-Long Registry Analysis of Prevalence and Risk Factors
Objective: This study aims to identify predictors of cognitive decline in cognitively normal Parkinson’s disease patients by analyzing the 10 years-long PD registry. Background: Cognitive…
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