Contribution of Dopamine Depletion, Cerebral Perfusion, and Cognition to Gait Dysfunction in Parkinson’s Disease
Objective: To explore the potential contribution of dopamine loss, perfusion deficit, and cognition to spatiotemporal gait parameters in patients with Parkinson's disease (PD). Background: Gait…Sub-grouping of Parkinson’s disease based on thalamic subnuclei volume
Objective: We aimed to categorize Parkinson’s disease (PD) using k-means clustering based on thalamic subnuclei volumes measured by structural magnetic resonance imaging (sMRI). Background: The…Levodopa mediated normalization of cerebello-thalamo-cortical GABA and Glutamate in Parkinson’s disease
Objective: This study aims to evaluate the effect of levodopa on cerebello-thalamo-cortical (CTC) gamma-aminobutyric acid (GABA) and glutamate in patients with Parkinson’s disease (PD) using…Evaluation of swallow tail sign on 1.5 Tesla Magnetic Resonance Imaging in Parkinson´s disease patients in a tertiary hospital
Objective: To evaluate the swallow tail sign in 1.5 Tesla magnetic resonance imaging (MRI) scans of patients diagnosed with Parkinson's disease (PD). Background: Nigrosome-1 appears…The Genetic Landscape of Parkinson’s Disease in African and Admixed Populations: Discovering Population-Specific Risk and Unveiling Etiological Insights
Objective: To perform the largest PD risk genome-wide association study (GWAS) in the African and African admixed populations. Background: Investigating the genetic foundation of Parkinson’s…Rare Variant Analysis of Sphingolipid-related Genes in Large Chinese Parkinson’ s Disease Cohorts
Objective: This study investigated the link between rare variants in sphingolipid-related genes and Parkinson’s disease (PD) in a Chinese mainland population. Background: Recently, growing evidence…Early-onset levodopa-responsive parkinsonism with cognitive impairment and head-bobbing dyskinesias associated with SYNJ1 and GBA variants of unknown significance
Objective: Describe the clinical and diagnostic findings of a patient with early-onset Parkinson’s Disease (EOPD) with homozygous variant of unknown significance (VUS) in the SYNJ1…European-Derived Parkinson’s Disease Polygenic Risk Score Model Is Associated With PD Status, UPDRS Score But Not Age At Onset Or Cognitive Impairment In An Egyptian PD Dataset
Objective: To assess the predictive ability of European-derived PD PRS model of 90 risk SNPs identified from the largest PD GWAS[1]in Egyptians and study its…Genome-wide Association Analyses Reveal Susceptibility Variants Linked to Parkinson’s Disease in the South African Population Using Inferred Global and Local Ancestry
Objective: The study aimed to investigate genetic risk factors for Parkinson’s disease (PD) in an admixed South African cohort using GWAS and local ancestry (LA)-GWAS…A Pan-Indian Genome-Wide Association Study of Parkinson’s Disease
Objective: To conduct the first pan-Indian genomic survey of PD across18 centres in India which included 4806 cases and 6363 controls. Background: The genetic architecture…
- « Previous Page
- 1
- …
- 169
- 170
- 171
- 172
- 173
- …
- 181
- Next Page »