MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    Gene-Caffeine Interaction in Parkinson’s Disease: A Case-Control Study of Alpha-synuclein SNPs

    BG. Yan, E. Ng, Y. Zhao, EK. Tan (Singapore, Singapore)

    Objective: Investigating the interaction between genetic susceptibility and caffeine intake in modulating Parkinson’s disease (PD) risk. Background: PD arises from a complex interplay of genetic…
  • 2025 International Congress

    Oculomotor Differences in PARK2 PD: a Study of Structured and Unstructured Eye Movements in an Irish Genetic Cohort

    A. Gallagher, C. O'Keeffe, J. Inocentes, M. Bradley, E. Donlon, B. Coe, B. White, R. Walsh, T. Lynch, R. Reilly, D. Munoz, C. Fearon (Dublin, Ireland)

    Objective: To identify and measure how eye movements differ between biallelic PARK2 carriers, carriers of a single PARK2 variant and non-carriers using structured and unstructured…
  • 2025 International Congress

    Effects of conventional and adaptive deep brain stimulation on systemic oxy-Inflammation in Parkinson’s Disease

    N. Maiorana, S. Marceglia, S. Mrakic-Sposta, A. Vezzoli, M. Guidetti, F. Martinelli Boneschi, T. Bocci, S. Oliveri, P. Signorelli, R. Ferrucci, A. Priori (Milan, Italy)

    Objective: This study investigates the impact of conventional (cDBS) and adaptive deep brain stimulation (aDBS) on systemic oxidative stress (OxS) and inflammation in Parkinson’s Disease…
  • 2025 International Congress

    Symptomatic Peri-Lead Oedema After Bilateral Subthalamic Nucleus Deep Brain Stimulation Surgery- Not All Cases Are Self-Limiting: A Case Series

    SS. Idris, O. Parras Granero, A. Chari, M. Krueger, H. Akram, J. Hyam, T. Foltynie, L. Zrinzo, P. Limousin (London, United Kingdom)

    Objective: To share 3 cases presented with seizure and encephalopathy after bilateral subthalamic nucleus deep brain stimulation surgery for Parkinson’s disease that requires removal of…
  • 2025 International Congress

    Real-World USA Outcomes in Patients Implanted with DBS Systems Capable of Directionality and Multiple Independent Current Control

    M. Okun, K. Foote, T. Zesiewicz, Y. Bezchlibnyk, A. Papanastassiou, O. Vaou, J. Carlson, J. Aldred, V. Krishna, B. Dalm, J. Durphy, J. Pilitsis, L. Verhagen Metman, S. Sani, D. Kern, S. Ojemann, R. Ramdhani, D. Weintraub, B. Sundaram, A. Siadati, D. Martinez, C. Zhao, M. Siddiqui, S. Tatter, L. Chen, R. Shivacharan, E. Goldberg (Gainesville, USA)

    Objective: This on-going registry seeks to collect/analyze real-world clinical outcomes out to 2-years follow-up in levodopa-responsive Parkinson's disease (PD) patients implanted with Deep Brain Stimulation…
  • 2025 International Congress

    A Retrospective, Multicenter, Harmonized Data Collection for Uncovering DBS Long-Term Axial Response

    M. Guidetti, S. Marceglia, P. Andrade, S. Babakry, MT. Barbe, T. Bocci, F. Bodlee, S. Bonvegna, H. Bronte-Stewart, S. Cascino, CE. Casselton, A. Fasano, M. Fumagalli, S. Giannoni-Luza, IU. Isaias, H. Jergas, MLF. Janssen, AM. Lozano, NV. Maiorana, N. Modugno, S. Oliveri, D. Pedrosa, M. Santilli, Y. Temel, L. Timmermann, D. Urso, V. Visser-Vandewalle, A. Priori (Milan, Italy)

    Objective: To determine pre-surgery (e.g., motor phenotype), during-surgery (e.g., electrodes' position), and post-surgery (e.g., stimulation parameters) factors predicting DBS-induced effects on axial symptoms in people…
  • 2025 International Congress

    The Impact of Bilateral GPi Deep Brain Stimulation on Non-Motor Symptoms in Parkinson’s Disease

    J. Lee, S. Jo, M. Choi, SJ. Chung (Goyang-si, Republic of Korea)

    Objective: This study aimed to evaluate how bilateral Globus Pallidus internus (GPi) Deep Brain Stimulation (DBS) affects non-motor symptoms in individuals diagnosed with Parkinson’s disease…
  • 2025 International Congress

    Association between corneal sensitivity with vision-related quality of life and ocular surface symptoms in Parkinson’s disease

    A. Camacho-Ordonez, M. Navarrete-Azuara, GR. Vera-Duarte, M. Rodriguez-Violante, A. Cervantes-Arriaga, AG. Alcocer-Salas, A. Ramirez-Miranda, EO. Graue-Hernandez (Mexico, Mexico)

    Objective: To evaluate the association between corneal sensitivity (CS) as measured by a non-contact Brill Engines esthesiometer, vision-related quality of life and ocular surface symptoms…
  • 2025 International Congress

    Impact of Sleep Disturbance and Early Morning OFF Symptoms on Health-Related Quality of Life in Advanced Parkinson’s Disease

    R. Pahwa, I. Malaty, K. Chaudhuri, J. Domingos, M. Heisen, P. Arija, D. Mohan, H. Penton, M. Kuharic, A. Lalla, Z. Baldwin, A. Shewale, C. Yan, M. Boeri (Gainesvile, USA)

    Objective: To quantify the impact of sleep disturbance (Sd) and early morning OFF (EMO) symptoms on health-related quality of life (HRQoL) in people with advanced…
  • 2025 International Congress

    Beyond Motor Symptoms: The Interplay Between Non-Motor Symptoms and Caregiver Challenges in Late-Stage Parkinson’s Disease

    D. Shah, A. Kothiala, D. Christian (Ahmedabad, India)

    Objective: To assess the relationship of non-motor (neuropsychiatric (NPS)) symptoms with the severity of motor symptoms of Parkinson’s Disease (PD). And to study the impact…
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