MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    European-Derived Parkinson’s Disease Polygenic Risk Score Model Is Associated With PD Status, UPDRS Score But Not Age At Onset Or Cognitive Impairment In An Egyptian PD Dataset

    S. El-Shafie, A. Nagano, I. Elsayed, E. Khedr, M. William, A. El-Hosseiny, A. Shalash, G. Fawi, M. Yousef, S. El-Jaafary, H. Lee, A. Jama, M. Koraym, Y. Salah, A. Atputhavadivel, S. Elfarrash, Y. Elsaid, A. Gabr, N. Shebl, L. Aly, N. Abdelwahhab, T. Belal, N. Elsayed, M. El-Gamal, S. Elgamal, S. Ragab, J. Mekky, H. Houlden, M. Salama, M. Rizig (Cairo, Egypt)

    Objective: To assess the predictive ability of European-derived PD PRS model of 90 risk SNPs identified from the largest PD GWAS[1]in Egyptians and study its…
  • 2025 International Congress

    Genome-wide Association Analyses Reveal Susceptibility Variants Linked to Parkinson’s Disease in the South African Population Using Inferred Global and Local Ancestry

    K. Step, T. Peixoto Leal, E. Waldo, L. Madula, Y. Swart, C. Hernández, S. Bandres-Ciga, J. Kim, I. Mata, S. Bardien (Cape Town, South Africa)

    Objective: The study aimed to investigate genetic risk factors for Parkinson’s disease (PD) in an admixed South African cohort using GWAS and local ancestry (LA)-GWAS…
  • 2025 International Congress

    A Pan-Indian Genome-Wide Association Study of Parkinson’s Disease

    A. Kishore, A. Sreelatha, A. Tenghe, R. Borgohain, D. Puthenveedu, R. Rajan, L. Ricardo, P. Pal, R. Mridula, M. Urulangod, R. Yadav, S. Mehta, H. Kumar, P. Agarwal, N. Kumar, P. Kukkle, S. Desai, M. Sharma (Tubingen, Germany)

    Objective: To conduct the first pan-Indian genomic survey of PD across18 centres in India which included 4806 cases and 6363 controls. Background: The genetic architecture…
  • 2025 International Congress

    Management of peri-lead cyst after Deep Brain Stimulation surgery: Review of literature and an illustrative case report

    V. Srinivasa Rangan, . (Hyderabad, India)

    Objective: Identification and management of an unusual complication following Deep Brain Stimulation surgery (DBS). Background: DBS is a well established treatment modality that has found…
  • 2025 International Congress

    Levodopa and DBS Produce Discordant Effects on Parkinsonian Features

    T. Lee, D. Ramesh, J. Perlmutter, J. Younce (Chapel Hill, USA)

    Objective: To compare the effect of levodopa vs deep brain stimulation on specific motor features of advanced Parkinson disease. Background: Levodopa (LD) is the gold…
  • 2025 International Congress

    A Data Visualization Tool to Improve Interpretation of MDS-UPDRS Results Post-DBS

    C. van Horne, G. Quintero, J. Hixson (Lexington, USA)

    Objective: To evaluate the potential of our previously developed data visualization platform for the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) as a…
  • 2025 International Congress

    Full-year Open-label Tracking of Adaptive Deep Brain Stimulation in Parkinson’s Disease in Two Patients: Considerations for Long-term Algorithm Maintenance

    J. Yao, M. Shcherbakova, A. Hahn, L. Hammer, S. Cernera, C. Oehrn, S. Little, P. Starr (San Francisco, USA)

    Objective: To assess the effects of chronic adaptive deep brain stimulation (aDBS) on motor symptoms and quality of life (QoL) and algorithm stability in two…
  • 2025 International Congress

    Analgesic Effect of Cannabidiol and Tetrahydrocannabinol(THC) on Pain Sensitivity in Reserpine Model of Parkinson’s Disease

    T. Muhammad, A. Isa, H. Tanko (Kaduna, Nigeria)

    Objective: The objectives of the study were to determine the effect of THC and CBD on:1. Thermal nociceptive threshold in reserpine induced Parkinson’s disease2. Mechanical…
  • 2025 International Congress

    Qigong Exercise on Nonmotor Symptoms in Parkinson’s Disease

    W. Liu, I. Smirnova, Z. Liu, K. Lyons, R. Pahwa (Kansas City, USA)

    Objective: This randomized controlled clinical trial examined the efficacy of a Qigong exercise on non-motor symptoms in people with Parkinson’s disease (PD). Background: Non-motor symptoms…
  • 2025 International Congress

    Application of Respiratory-Controlled Cardiopulmonary Coupling in Early Diagnosis of Parkinson’s Disease

    HF. Zheng, PH. Zhu, J. Wang (najing, China)

    Objective: Studies have shown that autonomic nervous  symptoms precede motor symptoms in  PD, making autonomic function assessment a potential tool for early PD diagnosis. This…
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