Disclosing CLIA certified genetic results within the LARGE-PD Cohort in Peru: Preliminary results of the PD GENEration study
Objective: To characterize the Peruvian Parkinson’s disease (PD) cohort within the Latin American Research Consortium on the GEnetics of Parkinson Disease (LARGE-PD) that received a…Analysis of LRRK2 Exonic Variants in Parkinson’s Disease in Chinese Population
Objective: To investigate the frequency of multiple LRRK2 variants in Parkinson's disease (PD) cohort, and to explore the effect of LRRK2 variants on the occurrence…Retinal Structural Changes in Parkinson’s Disease: insight into GBA1-Related PD and non-mutated PD
Objective: The study aims to explore differences in retinal thickness between GBA1-related Parkinson Disease (GBA1-PD) and non-mutated PD (NM-PD) and to analyze correlations between clinical…Association Analysis Between Genotypes and Disease Progression in Parkinson’s Disease
Objective: To investigate the relationship between genetic subtypes and disease progression in Early-Onset Parkinson’s Disease (EOPD) . Background: Genetic factors play a critical role in…Exome-wide Burden Analysis Identifies SYT10 as a Genetic Modifier of GBA-PD in UK Biobank
Objective: Identify potential genetic modifiers of GBA1 risk on Parkinson’s disease (PD). Background: GBA1 is a common genetic risk factor for PD. GBA1-carrying PD cases…Correlation between the microlesional effect of subthalamic deep brain stimulation and postoperative imaging in Parkinson’s disease
Objective: To characterize the clinical improvement associated with MLE and its temporal progression. In addition, to analyze postoperative images and investigate whether there is a…Optimization of Adaptive Deep Brain Stimulation Settings in Patients with Parkinson’s Disease
Objective: To evaluate the specific programming parameters of adaptive deep brain stimulation (aDBS) in Parkinson’s disease (PD) and identify the most effective settings for optimizing…Impact of Insurance and Risk Factors on DBS Outcomes
Objective: Assess the effect of insurance type on deep brain stimulation (DBS) outcomes, and identify risk factors for progression to assisted ambulation and dependency (home…Tracking The Role Of The Subthalamo-Temporal Network In Speech: A Deep Brain Stimulation-Electroencephalography Study
Objective: To identify deep brain stimulation (DBS)-related disruption of the subthalamic nucleus (STN)–temporal network as a possible source of STN-DBS induced dysarthria. Background: STN-DBS often…Evoked Resonant Neural Activity localises STN DBS programs more ventrally than clinician and imaging-guided methods in Parkinson’s disease
Objective: To compare 3 methods of localising STN DBS programs for PD; 1) clinical standard of care (SOC), 2) imaging-based programming (IBP), 3) novel algorithm…
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