Impaired glymphatic clearance independently contributes to poor outcomes in Parkinson’s disease
Objective: Clarify how glymphatic clearance impacts cognition in PD and its interaction with established imaging markers. Background: Impaired glymphatic clearance may contribute to pathological accumulations…Are Hallucinations in Parkinson’s Driven by Over-Reliance on Prior Information?
Objective: Test the validity of a theoretical model that visual hallucinations in Parkinson’s arise from over-reliance on prior information. Background: Parkinson’s hallucinations are common and…Duration of Illness and Response to Pimavanserin in Parkinson’s Disease Psychosis: Post-Hoc Analysis of Clinical Trial Data
Objective: To examine individual responses to pimavanserin in patients with Parkinson’s disease psychosis (PDP) initiating treatment <6 vs ≥6 months and <12 vs ≥12 months…Variations of Self-Perceived Cognitive Changes by Ethnicity in Parkinson’s Disease Patients
Objective: To study perceptions of cognitive function across ethnic groups by comparing a subjective rating with an objective assessment for patients with PD (PWP). Background:…CSF Biomarker-based Cognitive Trajectories in Parkinson’s Disease-Subjective Cognitive Decline
Objective: To investigate associations between CSF biomarkers and cognitive decline in Parkinson’s Disease-Subjective Cognitive Decline (PD-SCD). Background: The presence of cognitive complaints without objective cognitive…Distinguishing Functional and Essential Tremor from Tremor in Parkinson’s Disease using an objective comprehensive Motor Symptom Assessment Device
Objective: Our main aims were to 1) increase diagnostic accuracy and 2) reduce the time needed to reach the correct diagnosis in three disorders with…1-Year Outcomes for MDS-UPDRS Part I-IV and Clinical Impressions: Insights from a Large Real-World Prospective Study on de novo STN-DBS in Parkinson’s Disease
Objective: We present long-term prospective data from the Abbott DBS Post-Market Study of Outcomes for Indications Over Time (ADROIT, NCT04071847) in 233 patients from 41…Superior cluneal neuralgia in Parkinson’s disease: frequency and clinical features.
Objective: We investigated the frequency and clinical characteristics of superior cluneal neuralgia (SCN) in patients with Parkinson's disease (PD). Background: The superior cluneal nerve is…The Cleveland Clinic-Virtual Home Environment (CC-VHE): A Reliable Way to Trigger Freezing of Gait in Parkinson’s disease
Objective: To describe the development, safety, and efficacy of the Cleveland Clinic-Virtual Home Environment (CC-VHE) in provoking freezing of gait (FOG) in Parkinson’s disease (PD).…Developing Competency-Based Training Modules for Health Professionals in Parkinson’s Disease Management: A Review of Current Practices and Future Needs
Objective: To review existing competency-based training programs for health professionals in Parkinson’s disease (PD) management and identify future educational needs to enhance patient care. Background:…
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