CAP-003, a CNS-targeted IV-delivered AAV Gene Therapy Developed for Patients with Parkinson’s Disease associated with GBA1 Mutations
Objective: CAP-003 is a next-generation gene therapy candidate, comprising a novel brain-tropic capsid paired with hGBA1 cargo, that was developed for administration as a single…Deep Brain Stimulation and Lesional Surgery in Parkinson’s Disease: Our Experience in Santa Cruz de la Sierra, Bolivia
Objective: To evaluate the outcomes and complications of deep brain stimulation (DBS) and ablative surgery in patients with Parkinson’s disease (PD) in our center. Background:…Local field potential vs image guided programming: clinical trial for optimization the deep brain stimulation in Parkinson’s disease
Objective: To determine the most effective and efficient STN-DBS programming method in PD comparing LFP-GP and IGP focusing on motor improvement, quality of life and…Intraoperative Local Field Potentials and Selection of Deep Brain Stimulation Programming Contacts in Patients with Essential Tremor and Parkinson’s Disease
Objective: To report correlations of intraoperative local field potentials (LFPs) with longitudinal selection of optimal deep brain stimulation (DBS) programming contacts in patients with essential…Effectiveness and Outcomes of Deep Brain Stimulation revision surgery for Parkinson’s Disease
Objective: This study investigated the clinical characteristics, therapeutic efficacy and postoperative outcomes of Parkinson’s disease (PD) patients undergoing deep brain stimulation (DBS) revision surgery Background:…EEG Correlates of Orthostatic Hypotension in Parkinson’s Disease: Novel Biomarkers for Autonomic Failure
Objective: To identify potential EEG biomarkers associated with orthostatic hypotension in Parkinson Disease (PD) and evaluate their relationship with clinical measures of autonomic dysfunction. Background:…Individuals With a History of Traumatic Brain Injury Have a Higher Prodromal Burden Than Those Without Such a History
Objective: To characterise prodromal presentation in neurologically healthy individuals with and without a history of traumatic brain injury (TBI), compared to those with clinically diagnosed…Patients’ Perspective on Screening for Non-Motor Symptoms in Parkinson’s Disease, A QI Project
Objective: To assess deficiencies in patient care for individuals with Parkinson's disease in neurology clinics, with a particular focus on nonmotor symptoms. Background: While motor…Sex variations in non-motor symptoms (pain, fatigue, and nausea) in Parkinson’s disease patients: An analysis from the Mexican Parkinson’s Research Network
Objective: To compare pain, fatigue and nausea variables between sexes to see if there is a significant difference. Background: Patients with PD present motor and…Assessment of the Impact of Environmental Factors on Disease Progression in Parkinson’s Disease
Objective: This study evaluated the impact of environmental factors on the progression of Parkinson’s Disease (PD) in Texas using a claims-based algorithm to identify severity…
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