Impact of Patient-Specific Structural Connectivity of STN-DBS on Balance and Mobility – Pilot study
Objective: To evaluate the impact of patient-specific structural connectivity between VTA in STN targeting and SMA/preSMA on functional mobility improvements in PD patients undergoing DBS.…Description Genotype/phenotype of patients with Parkinson’s disease. Report of an Argentinean cohort included in the LARGE PD Consortium.
Objective: To characterize the genetic and phenotypic profile of Argentinean Parkinson's patients and contribute to the understanding of the genetic heterogeneity of this disease. Background:…Assessing the potential association of rs2298383 in ADORA2A as a predictor of Levodopa-Induced Dyskinesia in Latin American Parkinson’s Disease patients
Objective: To analyze the association between ADORA2A-rs2298383 and levodopa induced dyskinesias (LID) in a cohort of Latin American Parkinson’s disease patients. Background: Previous evidence has…Prevalence and Characteristics of Glucocerebrosidase Genetic Variants in Nepalese Early-onset Parkinson’s Disease Patients
Objective: To evaluate the genotype and phenotype of early-onset Parkinson´s Disease (EOPD) in the Nepalese population. Background: A significant proportion of early-onset PD (EOPD) can…Clinical and neuro-imaging predictors of falls in PLA2G6-related Parkinsonism: a retrospective study
Objective: This study investigates clinical and neuroimaging predictors of recurrent falls and gait disturbances in PLA2G6-related Parkinsonism. Background: PLA2G6-related Parkinsonism is characterized by dystonia-parkinsonism, cerebellar…Insights into Ancestral Diversity in Parkinson’s Disease Risk: A Comparative Assessment of Polygenic Risk Scores
Objective: This study aims to provide a comprehensive assessment of PRS performance across ancestries and highlight the limitations of a “one-size-fits-all” approach to genetic risk…Large-scale genetic characterization of Parkinson’s disease in the African and African admixed populations
Objective: The influence of genetics has been primarily studied in European populations, limiting our understanding of the genetic landscape of PD in the African and…Automated Image-Guided Programming Algorithm Supports Clinicians During DBS Programming for Parkinson’s Disease Patients
Objective: To assess clinical outcomes of an acute automated image-guided programming (aIGP) algorithm in PD patients implanted with a deep brain stimulation (DBS) system. Background:…Efficacy and outcomes of deep brain stimulation in elderly Parkinson’s disease: An institutional based study
Objective: Advanced therapies like DBS have been approved modalities for PD. Most studies focused on age below 65, reporting improvement in motor symptoms with persistent…Eight-Year Outcome of Focused Ultrasound Thalamotomy in Tremor Dominant Parkinson’s Disease Patients
Objective: To assess the 8-year outcome of unilateral MRI guided focused ultrasound (MRgFUS) ventral intermediate nucleus thalamotomy in tremor dominant Parkinson's disease (TDPD) patients, with…
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