Detecting Parkinson’s Disease with Postural Sway via Single IMU and Machine Learning
Objective: To determine whether simple standing balance tasks, assessed using a single wearable inertial measurement unit (IMU), can effectively differentiate individuals with Parkinson’s disease (PD)…Biomarker and Clinical Correlates of Restless Legs Syndrome (RLS) in Parkinson’s Disease: A Paradoxical Hyperdopaminergic State
Objective: To examine the clinical and biomarker correlates of Restless legs syndrome (RLS) in Parkinson’s disease (PD). Background: RLS is more common in PD than…Exploring Swallowing Dysfunction, Quality of Life, and Caregiver Burden in Multiple System Atrophy
Objective: To investigate associations between swallowing-related symptoms and disease severity, quality of life, and caregiver burden in patients with MSA in a large UK-based cohort.…Does PET Imaging Modality Influence Artificial Intelligence Performance in Diagnosing Parkinson’s Disease? Diagnostic Test Accuracy Meta-analysis
Objective: To determine whether AI diagnostic performance for Parkinson’s disease differs across PET imaging platforms Background: PET-based artificial intelligence (AI) has emerged as a promising…Bridging Genetics and Precision Medicine in Parkinson’s Disease through GP2: Translating Genetic Risk into Trial-Eligible GBA1 and LRRK2 Cohorts
Objective: To advance precision medicine in Parkinson’s disease (PD) by integrating large-scale clinico-genetic data from diverse populations worldwide and establishing a framework to characterize individuals…Genetic analysis of Mongolian patients with Parkinson’s Disease
Objective: To investigate the distribution of genetic variants among Mongolian patients with Parkinson’s disease within the framework of the international GP2 project MONPAR study .…Aerva Lanata Decoction Alleviates Neuroinflammation And Locomotor Dysfunction In Parkinson Model
Objective: The study focussed on the protective effects of decoction of aerial parts of the Aerva lanata against neuroinflammation, oxidative stress and locomotor deficits against…Comparison of Non-Motor Outcomes after Subthalamic Nucleus versus Globus Pallidus Internus Deep Brain Stimulation in Parkinson’s disease
Objective: To compare non-motor symptom outcomes after globus pallidus internus (GPi) versus subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson’s disease (PD). Background: Non-motor…Beyond the “best contact”: correlation of ai-guided dbs contact distribution and subthalamic nucleus beta physiology in parkinson’s disease patients
Objective: We hypothesized that optimal stimulation setting may involve a muti-contact configuration rather than a single contact with the largest therapeutic window (TW). We aimed…Safindream Safinamide as First Add On to Levodopa Improves Nonmotor Symptoms in Parkinson disease A Prospective Real World Study
Objective: To evaluate the real-world effectiveness of safinamide on non-motor symptoms, sleep disturbances, and mood in patients with Parkinson's disease receiving safinamide as the first…
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