Behavioral Phenotype of a Mouse Model of Mixed Movement Disorders Linked to ADCY5
Objective: To define the motor and non-motor phenotypic features of a novel Adcy5R419W mouse line [1] and validate it as an integrated model of human mixed movement disorders…Cannabis-based Oil for Pain and Other Non-motor Symptoms in Parkinson’s Disease: a Randomized Controlled Trial
Objective: To assess the safety, tolerance, and effectiveness of an oil extract of Cannabis sativa L. on pain and other non-motor symptoms (NMS) in people…Real-World Clinical Outcomes and Patient Experience Following Hybrid DBS Conversion to a Neurostimulator with Advanced Current Steering
Objective: In this report, we describe preliminary real-world clinical outcomes and patient experience following hybrid DBS conversion procedures at our center. Background: Hybrid replacement procedures…Delayed-Onset Rapidly Progressive Parkinsonism After BCMA×CD3 Bispecific Antibody Therapy: A Case Report
Objective: To describe a delayed-onset rapidly progressive parkinsonian syndrome with encephalopathy following BCMA×CD3 bispecific antibody therapy. Background: B-cell maturation antigen (BCMA) × CD3 bispecific antibodies…Neuroprotective Effects of Curcumin on Hippocampal-PPN Circuitry in a Rotenone-Induced Rat Model of Parkinson’s Disease
Objective: This study investigated the neuroprotective effects of curcumin on the hippocampal-pedunculopontine nucleus (PPN) axis in a rotenone-induced rat model of PD. Background: Parkinson’s disease…Predictors of Severity of Psychosis in Parkinson’s Disease: A 3-year longitudinal cohort study
Objective: To determine which disease-related variables are independently associated with severity of psychosis in Parkinson’s Disease. Background: Parkinson’s disease (PD) is a multisystem disorder in…Risk of Ischemic Cerebrovascular Events in Patients with Deep Brain Stimulation for Parkinson’s Disease: A Cohort Study
Objective: To longitudinally assess the risk of ischemic cerebrovascular events in patients undergoing DBS Background: Longitudinal data on the potential impact of DBS on long-term…Association Between Step Count Change Rate During Dual Task Timed Up and Go and Balance Components in Parkinson’s Disease
Objective: To identify balance components associated with the step count change rate during dual task Timed Up and Go in patients with Parkinson’s disease Background:…Skin Biopsy for Phosphorylated Alpha-Synuclein and DAT Imaging in Patients Diagnosed with Psychogenic Parkinsonism
Objective: Objective:Describe the results of skin biopsy for phosphorylated alpha-synuclein (P-SYN) and dopamine transporter (DAT) imaging in patients previously diagnosed with psychogenic parkinsonism (PP) and…Micrographia in Parkinson’s Disease and Multiple System Atrophy: A Quantitative Tablet-Based Handwriting Study
Objective: To evaluate the relative contributions of cognitive and motor factors to handwriting performance in patients with MSA and PD using quantitative tablet-based tasks. Background:…
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