Expanded Parkinson’s Disease GWAS in African Ancestry Populations Identifies Novel Risk Loci and Precision Medicine Targets
Objective: To conduct the largest genome-wide association study (GWAS) of Parkinson's disease (PD) in African (AFR) and African admixed (AAC) ancestry populations to identify ancestry-specific…Effect Of Low Frequency rTMS on Functional Tremor – Objective Evidence From A Single-Session And Longitudinal Observations
Objective: 1. To characterise electrophysiological features of functional tremor during cognitive and motor tasks.2. To evaluate immediate and longitudinal effects of low-frequency rTMS on tremor…Clinical Outcome Assessments for Psychiatric Manifestations in Dystonia: Systematic Review, Critique, and Recommendations
Objective: An International Parkinson and Movement Disorder Society subcommittee aimed to assess the quality of severity and screening instruments for depression, anxiety, apathy, OCD, mania,…Multisite high-definition gamma-tACS combined with rhythmic auditory cued gait enhances network efficiency in patients with Parkinson’s disease
Objective: The study aimed to determine whether high-definition gamma-tACS (hd-γtACS) delivered over the posterior parietal cortex (PPC)-primary motor cortex (M1) and cerebellum (CB)-M1 pathways during…Predicting Levodopa Responsiveness in Early Parkinson’s Disease Using Neural Perturbation Inference-Based Effective Connectivity
Objective: To investigate the brain network mechanisms underlying individual variability in levodopa responsiveness in Parkinson’s disease (PD) and to evaluate the predictive value of baseline…Genetic risk factors reduce the risk of diabetes mellitus in Parkinsons disease
Objective: To determine if LRRK2 variants are able to reduce the diabetes associated risk in Parkinsons disease Background: Leucine-rich repeat kinase 2 (LRRK2) mutations are…Microstructural and functional abnormalities of Amygdala subregions in Parkinson’s Disease with impulse control disorder
Objective: To investigate amygdala subregional alterations associated with impulse control disorders (ICD) in Parkinson’s disease (PD) and to clarify the mechanistic role of the superficial…Long-term therapeutic effects of repetitive transcranial magnetic stimulation combined with lidocaine injection (rTMS-LI) in dystonia
Objective: To investigate whether repetitive transcranial magnetic stimulation (rTMS) immediately followed by lidocaine injection (rTMS-LI) exerts disease-modifying or curative effects in dystonia. Background: We previously…Strategies for Participant Retainment in Large Observational Studies in Movement Disorders: a Single Centre Experience
Objective: To explore common reasons for participant attrition and recruitment barriers in observational studies in people affected by movement disorders.To explore common reasons for participant…Response to symptomatic therapy in Primary Brain Calcification: a cohort survey
Objective: To assess therapy response in a PBC cohort Background: Primary Brain Calcification (PBC) is a neurodegenerative disorder characterized by calcium deposition in the brain…
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