Genetic Landscape of Hereditary Ataxia in a Highly Consanguineous Population: A Nationwide Multicenter Study
Objective: To characterize the genetic spectrum and inheritance patterns of hereditary ataxia in a large cohort from Saudi Arabia, a population with a high rate…Effects of Psychiatric Symptoms on Dystonia Risk: a Prospective Cohort and Mendelian Randomization Study
Objective: To investigate the association between psychiatric symptoms and the risk of dystonia, and to explore potential causal effects using Mendelian randomization (MR). Background: Psychiatric…Comparison of Subcortical Brain Volumes in Different At-risk Cohorts of Parkinson’s Disease – Preliminary Data from the MUMFORD Study.
Objective: The overall aim of the study is to identify MRI markers that best distinguish between at-risk cohorts for Parkinson’s disease (PD) and healthy controls.…Feasibility study of a portable medical device, the Neuromotor pen, as a screening tool for Parkinson’s disease in a rural northern Tanzania
Objective: To evaluate the feasibility and acceptability of the Neuromotor pen (NMP) as a screening tool for Parkinson’s disease in a rural Tanzanian population. Background:…Network determinants of stimulation-induced speech impairment after subthalamic DBS in Parkinson’s disease
Objective: To delineate hemisphere-specific, local, and network-level mechanisms underlying stimulation-induced speech impairment after subthalamic deep brain stimulation (STN-DBS). Background: STN-DBS can improve but also worsen…Mood Motor Interactions in Parkinson Disease Clinical Associations and Neurobiological Mechanisms
Objective: To systematically map and synthesize clinical and neurobiological evidence examining associations between mood symptoms and motor dysfunction in Parkinson disease (PD), with emphasis on…A Novel paradigm for the recording of col-cap movements and muscle activity in Cervical Dystonia
Objective: We developed a protocol combining multi-muscle surface electromyography (sEMG) and kinematic analysis to characterise cervical muscle activity and head-neck-trunk movement patterns in CD after…Automatic Detection of Freezing of Gait from Simple, 2D Video Recordings in Complex Clinical Environments
Objective: To develop and validate a robust, video-based framework for automatic detection of freezing of gait (FOG) from conventional, simple 2D video recordings in clinically…Clinical Outcomes of Globus Pallidus Interna Deep Brain Stimulation in Primary and Secondary Dystonia: A Single-Center Experience
Objective: To evaluate motor and disability outcomes following GPi-DBS in a mixed cohort of primary and secondary dystonia patients treated from a tertiary referral center…Ipsilateral chorea due to thalamic hemorrhage: insights into network mechanisms of post-stroke hyperkinetic disorders
Objective: To report a case of ipsilateral chorea secondary to thalamic hemorrhage and discuss neurophysiological mechanisms of hyperkinetic movement disorders Background: Cerebrovascular disease accounts for…
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