Plasma Proteomics in PSP
Objective: We implemented an unbiased proximity extension proteomics assay to identify novel plasma PSP biomarkers. Background: Blood-based biomarkers can help to support non-invasive early diagnosis…Various Levodopa Formulation effects on Local Field Potentials in Parkinson’s Disease
Objective: To describe the electrophysiological changes that occur in the brain with the use of foscarbidopa-foslevodopa and compare it to other common formulations of levodopa…Modulatory effects of bacterial-derived serine protease on pathological α-synuclein fibrillation in vitro
Objective: To investigate the modulatory effects of bacterial-derived proteins on the pathological aggregation of α-synuclein (α-syn) Background: Aggregation of α-syn into toxic oligomers and protofibrils…Motor Network Neurophysiological (TMS-EEG) Markers as Predictors of Long-Term Outcomes Following Ventriculoperitoneal Shunt in Normal Pressure Hydrocephalus
Objective: Assess the ability of Delphi-MD (TMS-evoked potential (TEP)-based test) to predict long-term (over one year) response to VPS as an ancillary tool to improve decision-making. Background:…Passive smartphone-based tremor quantification in essential tremor
Objective: To develop and evaluate the accuracy of a passive smartphone-based method for detecting and quantifying essential tremor (ET) severity. Background: ET is among the…The Use of Digital Tools for Parkinson’s Phenotype Stratification to Improve Patients’ Selection for Advanced Therapies
Objective: Leveraging multimodal patient data to identify distinct multidimensional subtypes of Parkinson’s Disease and improve patient selection for appropriate advanced therapies. Background: The management of Parkinson’s condition is becoming increasingly complex and demanding as the ageing population rises. The NHSE10…Exercise and SUTT: A 9-week randomized, double-blinded, controlled intervention on Parkinsonian Gait.
Objective: To determine the effect of exercise combined with self-initiated unclassified therapeutic tremors (SUTT), over 9 weeks, compared to exercise-alone, on gait in people with…Redefining Anatomical Boundaries, An Atypical Case of MV-PLUS with Supratentorial extension.
Objective: To report the first case of Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance (MV-PLUS) with atypical supratentorial temporal extension, expanding the known…Neural Control of Real-Time Walking in people with Parkinson’s disease
Objective: To study the neural activity related to real-time walking in people with Parkinson’s (PwP) using a novel [18F]fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET) protocol and…Levels of cytokines in the cerebrospinal fluid of patients depending on the stages of Parkinson’s disease
Objective: To study of cytokine levels in serum and cerebrospinal fluid of patients with different stages of PD. Background: The clinical course of Parkinson's disease…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.