Monitoring oxidative stress and progression to cell death: From secretome to blood diagnosis
Objective: To achieve a comprehensive method able to distinguish the secretome changes caused by oxidative stress regulation or induction of cell death, and thus be…Histochemical evaluation of the effect of vitamin E on cyanide–induced damage on the prefrontal cortex of Sprague Dawley rats
Objective: To determine the histochemical evaluation of the effect of Vitamin E on Cyanide – induced damage on the Prefrontal cortex of Sprague Dawley Rats.…Genome-wide bioinformatic analysis of Parkinson’s disease: A focus on neuronal health maintenance
Objective: To scan the human genome for genes involved in neuronal health maintenance in Parkinson's disease (PD). Background: An enormous number of genes and pathways…Intracerebroventricular D-galactose injection provokes motor coordination impairment and cerebellar damage in Wistar rats
Objective: The present study was performed to investigate the effect of galactose (GAL) (at concentration in the brain, found in classical galactosemia) on motor coordination…Physical training prevents depressive-like behavior and bdnf decrease in an animal model of Parkinson’s disease
Objective: The aim of this study was to investigate the effects of two types of physical training on depressive-like behavior and pro-BDNF, BDNF and its…The effects of viral priming on neurotoxin induced neurodegeneration and synapse dysfunction in cell culture models relevant to Parkinson’s disease
Objective: To investigate the effects of viral innate immune activation on neurodegeneration and synaptic protein expression in dopaminergic (DA)-like neurons following treatment with Parkinson's disease…ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways
Objective: Endosomal sorting required for transport (ESCRT) orchestrates endo-lysosomal soring of ubiquitinated proteins, multivesicular body formation. The aim of this study is to elucidate the…Curcumin supplementation improves motor dysfunction in lipopolysaccharide induced Parkinon’s disease model: Possible biochemical, neurochemical and immunohistochemical alterations in rats
Objective: In the present study potential neuroprotective effects of curcumin were tested to determine if they could help to minimize microglia–mediated damage in single intranigral…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.