Movement disorder associated with 3-Idroxyisobutyryl-Coa hydrolase (HIBCH) deficiency
Objective: To describe an early onset movement disorder due to impairment of valine metabolism. Background: HIBCH deficiency is a rare inborn error of valine metabolism…Phosphodiesterases and striatal pathways in Parkinson’s disease
Objective: To use phosphodiesterase (PDE)10A ([11C]IMA107) and PDE4 ([11C]Rolipram) positron emission tomography (PET) molecular imaging combined with diffusion tensor imaging (DTI) based probabilistic tractography to explore the expression…Vascular hemiballismus due to a lentiform nucleus infarct
Objective: The aim of this study is to present a case of right hemiballism due to an ischemia located in the left lentiform nucleus. Background:…Familial idiopathic basal ganglia calcification with novel SLC20A2 gene variant
Objective: Describe a family with brain calcifications related to new pathogenic variant of SLC20A2 gene. Background: Three genes are associated with the rare occurrence of autosomal…F-18-DOPA-PET predicts impulsive behavior under dopaminergic therapy in Parkinson patients
Objective: The aim of this study is to investigate the influence of the intensity of dopaminergic projections to the ventral striatum (VS) measured with F-18-DOPA-PET…Measuring temporal irregularity in spiral drawings of patients with Parkinson’s disease
Objective: The aim of this work is to evaluate clinimetric properties of a method for measuring Parkinson’s disease (PD) upper limb temporal irregularities during spiral…Resting state functional connectivity in PD patients with and without Freezing of gait
Objective: To investigate resting state functional connectivity (rsFC) abnormalities in patients with Parkinson's disease (PD), either with (PD-FOG) or without freezing of gait (PD no-FOG). …Assessment of new technology in deep brain stimulation technology: what are the anticipated benefits?
Objective: To assess the ability of directional DBS leads and stimulation field shaping to provide more precisely targeted therapy. Background: Deep brain stimulation (DBS) has…Serotonergic, Dopaminergic Disruptions and Related Non-Motor Features Throughout the Course of Parkinson’s Disease: A Transversal PET Study
Objective: To explore the progression of DA and 5-HT lesions during the course of Parkinson’s disease (PD) and their respective contribution to the pathogenesis of…Circadian and Homeostatic Modulation of Multi-unit Activity in Dopaminergic and Striatal Structures
Objective: The aim of this study is to investigate the circadian and homeostatic modulation of the multi-unit activity of dopamineric and striatal neuronal structures. Background:…
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