Automatic assessment of tic expression using selfie-video
Objective: To create an automatic objective measure for quantifying tic expression and modulation in natural behavioral settings. Background: Tourette syndrome (TS) is characterized by the…Evoking Parkinsonism in Mice by a Pharmacological Approach Combined with Targeted Viral-based Manipulations of Neuronal Ensembles
Objective: We implement a pharmacological approach for eliciting dopamine deprivation using transient blockage of dopamine signaling to replicate core parkinsonian motor symptoms. Background: Parkinson’s disease…Dysconnectivity of the Parafascicular Nucleus in Parkinson’s Disease
Objective: The present study aimed to investigate the functional alterations of the parafascicular nucleus (Pf) projections in Parkinson’s disease (PD) patients. Background: Recent animal model…Exome sequencing of 584 Chinese proband with brain calcification
Objective: The aim of this study is to evaluate the diagnostic value of whole exome sequencing in Chinese patients with brain calcification, and to provide exome sequencing-based insights into the genetic…Uremic encephalopathy (UE) mimicking acute bulbar stroke with progression from bradykinesia to choreic movements in a diabetic patient undergoing hemodialysis: A case report
Objective: To present a case of uremic striatopallidal syndrome manifested by both hypo-and hyperkinetic extrapyramidal movements. Background: UE is an uncommon neurologic complication encountered in…Diabetic striatopathy presenting without hyperkinetic movements
Objective: To demonstrate a case of Diabetic striatopathy presenting without hyperkinetic movements Background: Diabetic striatopathy is an uncommon neurological complication associated with poorly controlled Diabetes Mellitus…Huntingtonism and bilateral basal ganglia hypointensity in a male with an XK variant but no McLeod red cell phenotype
Objective: To report a novel variant of XK without the characteristic RBC phenotype Background: XK disease (previously called McLeod Syndrome) is a rare X-linked disorder…Spectrum of hyperkinetic movement disorders in a Tunisian Cohort: an observational study
Objective: Recall clinical situations of hyperkinetic movement disorders (HMD) in a Tunisian cohort. Background: HMD result from a dysfunction of the basal ganglia(BG) and are…Levodopa-induced dyskinesia and Huntington’s chorea: link to current motor control theories
Objective: Determine if there is a motor control hypothesis that could explain movement kinematics of Huntington’s disease (HD) chorea and Parkinson’s disease (PD) levodopa-induced dyskinesia…Alterations in Cortico-basal ganglia Directed Connectivity in Parkinsonism and during Therapeutic STN DBS
Objective: Characterize the changes in oscillatory activity and connectivity in the basal ganglia thalamocortical (BGTC) network after induction of parkinsonian and during therapeutic deep brain…
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