Parkinsonism alters directed connectivity in the cortico-subthalamo-pallidal circuit
Objective: To characterize how parkinsonism alters directed connectivity across the motor cortex (M1), subthalamic nucleus (STN), and internal segment of the globus pallidus (GPi). Background:…Hemichorea revealing a putaminal cavernous angioma
Objective: Reporting an exceptional case of progrssive hemichorea revealing a putaminal cavernous angioma Background: Hemichorea is a rare movement disorder (MD) (0.7% of all MD)…Dorsolateral striatal neuronal activity in a rat model of Parkinson`s disease with levodopa-induced dyskinesias
Objective: This study aimed to investigate the firing properties of fast spiking interneurons (FSIs) and medium spiny neurons (MSNs) of the dorsomedial striatum (DLStr) and…Sydenham’s chorea: Clinical features and treatment outcome
Objective: To study the clinical features, investigations and treatment outcome in Sydenham’s chorea patients. Background: Sydenham’s chorea is one of the major clinical manifestations of…Co-administration of levodopa and zonisamide reduces the serotonin transporter expression in a rat model of Parkinson’s disease
Objective: To investigate the change of striatal serotonergic system according to the administration of levodopa and zonisamide (ZNS) on the striatal serotonergic system, we analyzed the…Genetic defects causing complex movement disorders and basal ganglia degeneration in childhood
Objective: To characterize genotype–phenotype correlations in basal ganglia degeneration (BGD) in childhood. Background: BGD in childhood causes movement disorders, neurodevelopmental dysfunction and long-lasting severe disability.…Basal Ganglionic Lesions in Egyptian Children: Radiological Findings in Correlation with Etiology and Clinical Manifestations
Objective: to determine the etiology of basal ganglionic disorders in a sample of Egyptian children. Background: In childhood, the metabolic activity of the basal ganglia…Movement disorders in mitochondrial disease: Radio clinical correlation in pediatric patients
Objective: Investigate the clinical features of movement disorders (MD), as well as brain imaging findings, in order to identify a radio-clinical correlation in mitochondrial diseases…Movement disorder associated with 3-Idroxyisobutyryl-Coa hydrolase (HIBCH) deficiency
Objective: To describe an early onset movement disorder due to impairment of valine metabolism. Background: HIBCH deficiency is a rare inborn error of valine metabolism…Subthalamic neuromodulation restores motor learning in Parkinson’s disease
Objective: The aims of the present study were to (i) investigate the effect of subthalamic deep brain stimulation (STN-DBS) on motor learning in Parkinson’s disease…
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