Combination Therapy of Ellagic Acid and Mucuna Pruriens Seeds Extract Improves Rotenone Induced Behavioural, Oxidative and Mitochondrial Deficits in Mice Model of Parkinson’s Disease
Objective: The present study was designed in order to explore the possible synergistic effect of two highly naturally occurring bio-active compounds viz. Ellagic acid (EA)…Erotophonophilia and severe impulse control disorder in a patient with Parkinson’s disease
Objective: N/A Background: Paraphilia a form of hyper sexuality is a rare complication of dopaminergic drugs used in the treatment of Parkinson's disease (PD). We…Oral treatment with sphingosine-1-phosphate receptors modulator prevents Parkinson symptoms concomitantly to reduced brain inflammation in MPTP mouse models
Objective: Here we explore the efficacy of an oral treatment with Fingolimod (FTY720), a selective sphingosine-1-phosphate receptors modulator, to prevent MPTP induced nigrostriatal loss and…Executive dysfunctions and behavioral changes in early drug-naïve patients with Parkinson’s disease
Objective: This study aims to explore the prevalence and onset age-related difference of executive dysfunctions and behavioral changes in drug-naïve patients with early stage of…Impulse control disorders could be accompanied by hypomanic state under intestinal levodopa infusion
Objective: To determine characteristics of parkinsonian patients under levodopa/carbidopa intestinal gel (LCIG) infusion who present impulse control disorders (ICDs). Background: ICDs may be induced by…Rasagiline as Adjunctive Therapy Induced Impulse Control Disorders in Parkinson’s Disease
Objective: In recent years there are an increasing number of impulse control disorders (ICDs), such as pathologic gambling, hypersexuality, compulsive shopping, compulsive eating, punding and…Non-motor symptoms in ACDY5-associated disease
Objective: To describe non-motor symptoms in a case of ACDY5-associated disease. Background: The hereditary dyskinesia syndrome caused by an ACDY5 mutation was first described in…Co-speech gestures in Parkinson’s disease (PD)
Objective: We develop an analytical description of co-speech gesture production in PD patients. Background: Communication and expressive behavior problems are frequent in PD patients (Duncan…VIT-D and Tics Movement Disorder
Objective: Tics is common childhood movement disorder, with classified variants , typically begin at around 4-5 years of age but often present lator at about…Noladin ether attenuates MPTP -induced motor deficit by abrogating pro-inflammatory cytokines and striatal neurochemical alterations in rats
Objective: The present study was designed to investigate the therapeutic potential of noladin ether- a putative endocannabinoid against MPTP-induced behavioral, biochemical and neurochemical alterations in…
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