Off-painfull state in Parkinson’s disease patients: A redflag of complulsive behavior. Data from a PET-FDG study
Objective: The aim of this study was to investigate the neural underpinnings of the dopaminergic dysregulation syndrome( DDS ) during the “off-phase”. Background: The DDS…Abrogation of Rotenone Induced Behavior, Biochemical and Mitochondrial Deficits in Mice by Curcumin and Ginkgo Biloba: New Combinational Therapy Approach for Parkinson’s Disease
Objective: This study was designed with the objective to find out the possible synergistic effect of Curcumin (Cur) and Methanolic extract of Ginkgo biloba (EGB)…No MPTP-induced behavioral deficits or Striatal field potential alterations in crossbreds of MPTP-susceptible and MPTP-resistant mice strains
Objective: To evaluate the electrophysiological and motor behavioural correlates of strain-dependent differential susceptibility of mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and the role of admixing thereon. Background:…Neuromodulatory propensity of Ginko biloba to offset rotenone induced behaviour and biochemical alteration
Objective: The aim of present study was to evaluate neuromodulatory propensity of Gingko Biloba in rotenone induced Mice Model of Parkinson Disease in terms of…α-synuclein aggregation and propagation in marmoset brains deteriorates its motor function
Objective: To confirm that α-synuclein aggregation and propagation in marmoset brains deteriorates its motor function. Background: Recently, the α-synuclein amyloid fibril is thought to be…Neuroprotective Effects of A Combination of Curcumin and Mucuna Prurience in Rotenone Induced Mice Model of Parkinson’s Disease
Objective: In the current study we have evaluated possible synergistic neuroprotective effect of two Poly-Phenols from Curcumin and Mucuna Prurience. The combine treatment of Curcumin…Correlation between mood and behavioral disorders and quality of life in patients with Parkinson’s disease
Objective: The aim of this study was to investigate if the mood and behavioral disorders could be correlate with quality of life in patients with…Combination Therapy of Ellagic Acid and Mucuna Pruriens Seeds Extract Improves Rotenone Induced Behavioural, Oxidative and Mitochondrial Deficits in Mice Model of Parkinson’s Disease
Objective: The present study was designed in order to explore the possible synergistic effect of two highly naturally occurring bio-active compounds viz. Ellagic acid (EA)…Erotophonophilia and severe impulse control disorder in a patient with Parkinson’s disease
Objective: N/A Background: Paraphilia a form of hyper sexuality is a rare complication of dopaminergic drugs used in the treatment of Parkinson's disease (PD). We…Oral treatment with sphingosine-1-phosphate receptors modulator prevents Parkinson symptoms concomitantly to reduced brain inflammation in MPTP mouse models
Objective: Here we explore the efficacy of an oral treatment with Fingolimod (FTY720), a selective sphingosine-1-phosphate receptors modulator, to prevent MPTP induced nigrostriatal loss and…
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