Exploring therapeutic viability of a non-dopaminergic target for Parkinson’s disease
Objective: Non-dopaminergic protein drug targets are of high interest to develop adjuvant treatments for currently insufficiently addressed symptoms of PD. RGS4, a regulator of G-protein…Cognitive and behavioral side effects in patients treated with droxidopa for neurogenic orthostatic hypotension
Objective: To describe adverse behavioral symptoms attributed to droxidopa therapy for neurogenic orthostatic hypotension (nOH). Background: Droxidopa, a norepinephrine (NE) precursor, improves symptoms of neurogenic…Smell perception and judgement in PD patients: Results of a study designed, conducted, analysed and reported by PD patients
Objective: The objective of this study was to investigate smell impairment in PD and the role of judgement in sensory accuracy. Background: The sense of…Neuropsychological correlates of impulse control disorders and punding in Parkinson´ s disease
Objective: To investigate the relationship between cognitive deficits, Impulse Control Disorders (ICDs) and Punding in Parkinson's disease (PD). Background: The neuropsychological correlates of ICDs and…Technology use and impulse control disorders (ICDs) in patients with Parkinson’s disease (PD)
Objective: To ascertain the prevalence of problematic technology use (Technology-related ICDs, Tech-ICDs) in patients with PD. Background: ICDs are a known complication of PD drugs…Volition and action control in Parkinson’s disease patients with impulsive-compulsive behaviour disorders
Objective: We aimed to explore different aspects of action control, assessing reward-related behaviour, inhibition (externally and internally triggered) and sense of agency in Parkinson's disease…
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