Electroconvulsive therapy for refractory psychiatric symptoms in GBA-related Parkinson disease patient
Objective: This case report aims to highlight the ECT as a promising option on refractory neuropsychiatric manifestations of PD. Background: In GBA-related PD, non-motor symptoms…Association between Alzheimer’s disease co-pathology and neuropsychiatric symptoms in Lewy body dementia
Objective: To identify the associations between Alzheimer Disease (AD) co-pathology and neuropsychiatric symptoms in Lewy body dementia (LBD). Background: Dementia with Lewy Bodies (DLB) and…HYPERSEXUAL DISORDER IN GBA-ASSOCIATED PARKINSON’S DISEASE: CASE REPORT
Objective: To describe a patient with PD and hypersexual disorder carrying a GBA variant. Background: Compulsive sexual behavior occurs in 4% of patients with Parkinson’s…Characterization of a mouse model of PDE10A-related autosomal-dominant movement disorder.
Objective: To characterize a newly generated mouse model of the movement disorder caused by PDE10A pathogenic mutation F300L. Background: Phosphodiesterase 10A (PDE10A) is a striatal…A case of Bainbridge-Ropers syndrome in a child.
Objective: This study describe the clinical case of Bainbridge-Ropers syndrome caused by the ASXL3 gene mutation. Background: Bainbridge-Ropers syndrome is an autosomal dominant disorder typically…Deep Brain Stimulation of Anterior Globus Pallidus internus Reduces Impulsivity in Parkinson’s Disease
Objective: To evaluate whether selective deep brain stimulation (DBS) stimulation of anterior region of globus pallidus internus (GPi) affects impulsivity in Parkinson’s Disease patients Background:…Neuroprotective and neuromodulatory properties of Olea purpurea leaf extract in MPTP intoxicated Parkinsonian rat model
Objective: This study aimed to isolate and characterize Olea purpurea leaf extract, and its neuroprotective effect in MPTP induced parkinsonian rat model. Background: Parkinson's disease (PD), also…Evaluation of the Body Weight Changes and Food Addiction in Parkinson’s Disease patient with Deep Brain Stimulation
Objective: The aim of this study is to evaluate Parkinson’s disease patient’s body weight changes after Deep Brain Stimulation (DBS) and to search the existence…Intrastriatal injection of alpha-synuclein preformed fibrils results in cognitive dysfunction and L-DOPA reversible sensorimotor impairments in rats
Objective: To determine the effect of intrastriatal injection of alpha-synuclein (aSyn) preformed fibrils (PFFs) on sensorimotor and non-motor function in rats. Background: The ideal animal…Impulse control disorders in Parkinson’s disease: A whole brain morphometric and diffusion tensor study
Objective: To study morphometric and structural connectivity changes in the mesocorticolimbic pathway associated with the occurrence of impulse control disorders in Parkinson's disease. Background: Impulse…
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