Self-report vs. informant-report of problematic behaviors using the Huntington’s Disease-Behavioral Questionnaire
Objective: To examine the utility of a new behavioral measure, the Huntington’s Disease–Behavioral Questionnaire (HD-BQ) (Hughes et al, 2023), in individuals with Huntington’s disease (HD).…Impact of dopamine replacement therapy on shame in Parkinson’s disease patients
Objective: This study aims to investigate the effect of dopaminergic replacement therapy (DRT) on shame using emotional dynamic rating scales during ON and OFF-DRT states.…Evaluating the efficacy of dextromethorphan/quinidine (DM/Q) in treating irritability in Huntington’s disease
Objective: To prove the efficacy and safety of dextromethorphan/quinidine 20mg/10mg (Nuedexta®) in patients with irritability due to HD. Background: Irritability is one of HD's most…Needs and priorities of people with Parkinson’s and care partners regarding neuropsychiatric symptoms
Objective: To examine the experiences of people with Parkinson’s disease (PD) and care partners (CPs) regarding cognitive, mood, behavioral, and sleep issues. Background: Neuropsychiatric symptoms…Tramadol Induces Neuroinflammation, Mitochondrial Oxidative Stress, Neurotransmitters Dysbalanced and Produced Parkinson’s Disease Like Symptoms in Experimental Wistar Rats
Objective: The current study is designed to evaluate the possible neurotoxic effects of tramadol in Wistar rats. Background: Parkinson’s disease (PD) is a chronic neurodegenerative…Specific Parkinson’s disease phenotype in patients with long term PTSP
Objective: to describe possibly specific clinical phenotype of PD patients who suffered from long-term postraumatic-stress-disorders (PTSD Background: There is enough evidence about the relationship between…Diffusion imaging study of mild behavioral impairment in Parkinson’s disease.
Objective: Patients with Parkinson’s disease (PD) experience changes in behavior, personality, and cognition. Mild Behavioral Impairment (MBI) is a validated neurobehavioral syndrome that identifies a…Therapeutic effects of citral nanoliposome on Parkinson’s treatment in a rat model: Modulation via neurochemical, inflammatory and antioxidant pathways
Objective: The present study aimed to assess the effects of citral nanoliposome on Parkinson's treatment in a rat model. Background: Parkinson's disease is the most…Protective approach targeting NF-kB/ Nrf2 signaling and neuroinflammation using Apigenin in LPS induced Parkinsonism in experimental rats
Objective: 1. Apigenin as a protective strategy to prevent neuroinflammation in PD.2. To find behavioral, neurochemical and histopathological changes in LPS induced PD. Background: Parkinson’s…Cognitive and Motor aspects of a Brazilian population with Parkinson´s disease and Impulse Control Disorders and/or Related Behaviors – an observational study.
Objective: We analysed if Impulse Control Disorders (ICDs) and/or Related Behaviors (RBs) were associated with levodopa-induced dyskinesia (LIDs) in Brazilian patients with Parkinson´s disease (PD)…
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